Background: Oral and dental diseases experienced by Indonesians is recurrent apthous stomatitis with a national prevalence of 8.0%. Stress can afflict children, adolescents, adults and the elderly even in a school environment, so stress can happen to anyone, anywhere. People who experience stress result in decreased concentration ability, deteriorating health, depression and sleep disorders and even dental and oral health problems, one of which is recurrent aphthous stomatitis. Objective: To determine the relationship between academic stress and the incidence of recurrent aphthous stomatitis. Methodology: this type of analytic observational study with cross sectional design. The research was conducted on students of the Department of Dental Health, Jakarta Health Polytechnic I. Collecting data using an observation sheet for the incidence of recurrent aphthous stomatitis and a questionnaire to determine the level of academic stress. Data analysis using Chi-Square. Results: it was found that academic stress on the incidence of recurrent aphthous stomatitis showed the p-value was 0.047 (p <0.05). Conclusion: There is a significant relationship between academic stress and the incidence of recurrent aphthous stomatitis
Keywords: Academic stress, recurrent aphthous stomatitis