Hubungan Kualitas Air dengan Profil Metabolit Sekunder Ekstrak Daging Holohuria atra di Perairan Teluk Lampung dan Perairan Garut

Nurfitriani, Evi; Mulyani, Yeni; Agung, M. Untung Kurnia

doi:10.24198/jaki.v2i2.23423

Cited by 5 publications

(4 citation statements)

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“…These results are consistent with those of Putra et al (2016) and Prasetyana et al (2022). It should be highlighted, nonetheless, that environmental and geographic factors might cause variations in the secondary metabolite composition even within the same plant species (Katuuk et al, 2018;Agustina et al, 2016;Nurfitriani, 2016). Plant secondary metabolites provide the body with biological advantages and functions.…”

Section: Moringa Leaves Ethanol Extract (Mlee)mentioning

confidence: 99%

Antidiabetic Potential of Ethanol Extract from Moringa oleifera Leaves in Streptozotocin-Nicotinamide-Induced Female Mus musculus

Prakasita,

Theodora,

Susilowati

et al. 2024

Jurnal Biodjati

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Type 2 diabetes mellitus (DM) is a chronic metabolic disorder characterized by elevated blood glucose levels due to insulin resistance. Type 2 diabetes is considerably more prevalent than other forms (85–90%). The risk of type 2 diabetes is higher in women (53.2%). There is an urgent requirement for better and more affordable treatment options considering DM therapy is expensive and may have adverse health effects. The study's objective is to examine how acute toxicity, blood glucose levels, and body weight are affected by Moringa leaf ethanol extract (MLEE). Maceration was employed to eliminate the leaves of the moringa plant. Phytochemical screening was completed to assess the total flavonoid content and screen for alkaloids, flavonoids, phenolics, saponins, and tannins. Acute toxicity testing was performed following OECD guideline 423. Clinical symptoms of acute toxicity were observed every 30 minutes for the first 24 hours post-treatment, followed by observations every 24 hours up to 14 days. The estimated LD50 range was determined. Streptozotocin/ nicotinamide-induced female Mus musculus was administered to evaluate the antidiabetic potential of MLEE. Six groups of mice were utilized, which included a healthy control group (aquades not induced), a negative control group (induced aquades), a positive control group (induced glimepiride 0.8 mg/kg BW), and three treatment groups with varying dosages of MLEE (induced; 0, 100, and 150 mg/kg BW). A semi-auto chemical analyzer was employed on days 0 through 31 to determine blood glucose levels. An analytical digital balance was utilized to calculate the body weight. With a total flavonoid concentration of 20.75%, MLEE incorporated alkaloids, flavonoids, phenolics, saponins, and tannins. MLEE demonstrated a significant effect in lowering blood glucose levels at a dose of 100 mg/kg BW (P<0.05). A significant positive correlation has been identified between body weight and blood glucose levels (P<0.05).

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Section: Moringa Leaves Ethanol Extract (Mlee)mentioning

confidence: 99%

Antidiabetic Potential of Ethanol Extract from Moringa oleifera Leaves in Streptozotocin-Nicotinamide-Induced Female Mus musculus

Prakasita,

Theodora,

Susilowati

et al. 2024

Jurnal Biodjati

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“…Pertumbuhan tanaman sangat dipengaruhi oleh faktor genetik dan lingkungan tempat tumbuhnya (Katno, 2008). Diketahui nilai nutrisi yang berbeda pada tanaman dipengaruhi oleh iklim lingkungan, tingkat kematangan, masa panen dan karakteristik tanah di mana tanaman tersebut tumbuh (Nurfitriani, 2016). Kota Samarinda berada pada daerah dataran rendah.…”

Section: Tabel 1 Hasil Pengujian Parameter Simplisa Dan Ekstrak Etano...unclassified

PENGARUH TEMPAT TUMBUH TERHADAP PARAMETER MUTU SIMPLISIA DAN EKSTRAK ETANOL DAUN AFRIKA (Gymnanthemum amygdalinum (Delile) Sch.Bip.) YANG TUMBUH DI KABUPATEN BANDUNG DAN KOTA SAMARINDA

Erlisa Irawati Putri,

Livia Syafnir,

Kiki Mulkiya

2023

BCSP

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Daun Afrika adalah tumbuhan dengan nama latin (Gymnanthemum amygdalinum). Tanaman daun Afrika dapat ditanam di lokasi yang cerah dan lembab. Tanaman daun Afrika tumbuh di semua jenis tanah, namun daun Afrika tumbuh subur di tanah yang kaya humus. Penelitian ini bertujuan untuk mengetahui pengaruh perbedaan tempat tumbuh tanaman daun Afrika terhadap parameter mutu dan kandungan senyawa didalamnya. Ekstrak daun Afrika dibuat dengan metode maserasi menggunakan pelarut etanol 70%. Hasil yang diperoleh dari penelitian ini daun Afrika yang berasal dari Kota Samarinda memiliki rendemen sebesar 23,10% dan daun Afrika yang berasal dari Kabupaten Bandung memiliki rendemen sebesar 12,79%. Parameter simplisia maupun ekstrak yang dihasilkan antara kedua tanaman yang tumbuh di dua tempat berbeda tersebut memiliki perbedaan meliputi kadar abu, kadar air, susut pengeringan, kadar sari larut air dan kadar sari larut etanol. African leaf is a plant with the Latin name (Gymnanthemum amygdalinum). African deciduous plants can be grown in sunny and humid locations. African leaf plants grow in all types of soil, but African leaf thrives in humus-rich soil. This study aims to determine the influence of differences in the place where African leaf plants grow on the quality parameters and compound content in them. African leaf extract is made by maceration method using 70% ethanol solvent. The results obtained from this study African leaves from Samarinda City have a yield of 23.10% and African leaves from Bandung Regency have a yield of 12.79%. The parameters of simplisia and extract produced between the two plants that grow in two different places have differences including ash content, moisture content, drying shrinkage, water soluble juice content and ethanol soluble juice.

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“…Senyawa bioaktif diproduksi dari hasil metabolit sekunder saat berada pada kondisi tertekan. Nurfitriani et al (2019) menyatakan bahwa teripang Holothuria atra yang berasal dari perairan Garut memiliki komponen bioaktif yang berbeda dari perairan Lampung. Perairan Garut memiliki kondisi perairan cenderung dinamis dan ombak yang besar sehingga lebih memicu keadaan stres bagi teripang dibandingkan dengan perairan di sekitar Jepara yang merupakan Laut Jawa yang relatif tenang.…”

Section: Hasil Dan Pembahasan Karakteristik Rumput Laut Sargassum Polunclassified

Efektivitas bubur rumput laut Sargassum polycystum sebagai pembalur ikan nila (Oreochromis niloticus) untuk mempertahankan mutu

2020

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Tujuan penelitian ini yaitu menentukan proporsi terbaik bubur rumput laut dalam menghambat kemunduran mutu ikan nila. Proporsi bubur rumput laut yang digunakan yaitu 0; 12,5; 25; 50%. Parameter uji meliputi organoleptik, derajat keasaman, total mikroba, dan total volatile base (TVB). Penelitian ini meliputi preparasi sampel, analisis fitokimia, pembuatan proporsi bubur rumput laut, serta penentuan proporsi bubur rumput laut terbaik. Penelitian dilakukan pada suhu ruang dengan dua kali ulangan. Hasil analisis fitokimia ekstrak metanol menunjukkan bahwa S. polycystum mengandung senyawa alkaloid, steroid, flavonoid, fenol, dan tanin. Proporsi bubur rumput laut 25% merupakan perlakuan terbaik dalam mempertahankan mutu ikan nila hingga waktu penyimpanan jam ke-6. Semakin lama waktu penyimpanan maka ikan nila semakin mengalami kemunduran mutu.

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Hubungan Kualitas Air dengan Profil Metabolit Sekunder Ekstrak Daging Holohuria atra di Perairan Teluk Lampung dan Perairan Garut

Cited by 5 publications

References 0 publications

Antidiabetic Potential of Ethanol Extract from Moringa oleifera Leaves in Streptozotocin-Nicotinamide-Induced Female Mus musculus

Antidiabetic Potential of Ethanol Extract from Moringa oleifera Leaves in Streptozotocin-Nicotinamide-Induced Female Mus musculus

PENGARUH TEMPAT TUMBUH TERHADAP PARAMETER MUTU SIMPLISIA DAN EKSTRAK ETANOL DAUN AFRIKA (Gymnanthemum amygdalinum (Delile) Sch.Bip.) YANG TUMBUH DI KABUPATEN BANDUNG DAN KOTA SAMARINDA

Efektivitas bubur rumput laut Sargassum polycystum sebagai pembalur ikan nila (Oreochromis niloticus) untuk mempertahankan mutu

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