Hubungan kadar glukosa darah puasa dengan obesitas pada remaja di Kecamatan Bolangitang Barat Kabupaten Bolaang Mongondow Utara

Abstract

Obesity has become a serious problem world-wide. Obesity occurs due to the imbalance of intake and output energy. Thus, it is related with the incidence of insulin resistance and the disruption of glucose metabolism. This study was aimed to obtain the correlation between fasting blood sugar level and obesity in adolescents. This was an analytical study with a cross-sectional design. The results showed that the major category of subjects was obese I (38.33%). The highest percentage was normal blood sugar which was found in non-obese adolescent (96.8%). The Spearman correlation test showed a sweak correlation between obesity and fasting blood sugar level in adolescent (r=0.386; p=0.004). Conclusion: There was a significant weak correlation between fasting blood sugar level and obesity in adolescents.Keywords: obesity, fasting blood glucose, adolescent. Abstrak: Obesitas menjadi masalah di seluruh dunia baik di negara maju maupun negara berkembang, prevalensinya pun meningkat begitu pesat. Obesitas terjadi karena adanya ketidakseimbangan antara energi yang masuk dengan energi yang keluar. Obesitas berkaitan dengan terjadinya resitensi insulin dan gangguan metabolisme glukosa.Penelitian ini bertujuan untuk mengetahui hubungan kadar glukosa darah puasa dengan obesitas pada remaja di Kecamatan Bolangitang Barat Kabupaten Bolaang Mongondow Utara. Jenis penelitian ialah analitik dengan desain potong lintang. Hasil penelitian menunjukkan bahwa subjek penelitian terbanyak dalam kategori obes I (25,0-29,9 kg/m2) sebesar 38,33%. Kadar gula darah normal pada remaja non-obes dengan persentasi tertinggi (96,8%). Analisis korelasi Spearman pada kedua variabel memperoleh nilai koefisien korelasi r = 0,368 (p = 0,004). Simpulan: Terdapat hubungan bermakna yang lemah antara kadar gula darah puasa dan obesitas pada remaja. Kata kunci: obesitas, gula darah puasa, remaja

Associations Of Betatrophin Levels With Fasting Blood Glucose In Obese Females

“…Insulin resistance that occured can cause an increase in blood glucose levels (Clare et al, 2007). The results of previous study by Polli et al (2016) added that in a state of obesity there is a decrease in adiponectin and an increase in free fatty acids that are opposite to the effects of insulin, causing a decrease in insulin sensitivity or insulin resistance. Fatty acids and some other metabolic activates protein kinase and break the insulin signaling by increasing serine phosphorylation which is inhibitory of the insulin receptor substrate (IRS), thus causing insulin resistance.…”

Gambaran Glukosa Darah dan Glukosa Urin pada Dewasa Muda Berat Badan Lebih dan Obes

“…Peningkatan glukosa darah dipengaruhi oleh faktor IMT. Hal ini selaras dengan penelitian Polii et al 10 yang menyatakan pada keadaan obesitas terjadi penurunan adiponektin dan peningkatan asam lemak bebas yang tidak berlangsung sesuai kerja insulin sehingga terjadilah sensitifitas insulin dan berakhir pada resistensi insulin. Asam lemak dan beberapa metabolit dalam tubuh mengaktifkan protein kinase dan merusak sinyal insulin dengan menaikkan fosforilasi serin yang bersifat inhibisi dari insulin receptor substrate (IRS), sehingga menyebabkan resistensi insulin.…”

The Relation Between IGF-1 Levels and Fasting Blood Glucose in Obese Women

“…2 Obesity is a problem all over the world both in developed and developing countries, with prevalence rates increasing so rapidly. 3 Obesity is a dangerous condition, with prevalence of 20% . 4 Based on data from the World Health Organization (WHO) (2016) that more than 1.9 billion people aged over 18 years old are overweight and 650 million of them are obese.…”

“…9 Obesity is one of the causes of metabolic disorders such as insulin resistance, resulting in an increase in blood glucose levels. 3,4 In addition, obesity also affects the secretion of Insuline-Like Growth Factor-1 (IGF-1). In obesity, hyper-insulinemia due to peripheral insulin resistance binds to Insuline-Like Growth Factor-1 Receptors (IGF-1R), resulting in decreased circulation of Insulin-Like Growth Factor Binding Protein-1 (IGFBP-1) resulting in IGF-1 levels free in the blood increases.…”

“…Based on the results of previous studies, it's showed a significant correlation between obesity and fasting blood glucose (FBG). 3 Insulin plays an important role in maintaining normal blood glucose levels, and IGF-I exerts a complementary effect on glucose regulation. 1 IGF-1 levels indicate value the rate is lower in obese women than in overweight.…”