HTLV-I/II seroprevalence in 55 Brazilian patients with idiopathic uveitis

Pinheiro, S. R.; Carneiro-Proietti, Anna Bárbara F.; Lima‐Martins, Maria Virginia C.; Proietti, Fernando Augusto; Pereira, Alexandre A.; Oréfice, Fernando

doi:10.1590/s0037-86821996000400014

Cited by 8 publications

(7 citation statements)

References 4 publications

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“…30 Our seroprevalence survey of HTLV-1 infection in patients with uveitis of undetermined origin showed a 1.8% seropositivity prevalence compared with none in patients with uveitis of determined origin. Other studies have found a seroprevalence of 2 (3.6%) of 55 Brazilian patients with uveitis of unknown origin 31 and a local seroprevalence in blood donors of 0.32%. 20 The 2 patients who were seropositive for HTLV-1 in the latter series were 12 and 19 years of age, and both had anterior uveitis.…”

Section: Seroepidemiological Surveymentioning

confidence: 88%

Human T-Cell Lymphotropic Virus Type 1 Infection and Ocular Manifestations in São Paulo, Brazil

Yamamoto¹

1999

Arch Ophthalmol

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Although human T-cell lymphotropic virus type 1 (HTLV-1)-associated uveitis has been well recognized in Japan, related studies in Brazil are scarce. We performed a serologic survey for HTLV-1 infection among patients with uveitis and investigated the ocular findings in HTLV-1-asymptomatic carriers.Methods: One hundred ninety serum samples from patients with uveitis of determined (n = 137) and undetermined origins (n = 53

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Section: Seroepidemiological Surveymentioning

confidence: 88%

Human T-Cell Lymphotropic Virus Type 1 Infection and Ocular Manifestations in São Paulo, Brazil

Yamamoto¹

1999

Arch Ophthalmol

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“…HTLV-I seroprevalences of 35.4-44.8% were found in patients with uveitis of unknown etiology in Southwestern Japan, much higher than HTLV-I prevalence in the local population (Mochizuki et al, 1992). In studies of other areas lower seropositivity was found (Goto et al, 1994;Pinheiro et al, 1996;Yamamoto et al, 1999).…”

Section: Uveitis Arthritis and Other Autoimmune Diseasesmentioning

confidence: 97%

“…It has been convincingly associated with adult T-cell leukemia/lymphoma (ATL) (Poiesz et al, 1980;Hinuma et al, 1981;Miyoshi et al, 1981b;Yoshida et al, 1984;Takatsuki et al, 1985a, b), HAM/TSP (Cruikshank, 1956;Gessain et al, 1985;RodgersJohnson et al, 1985;Osame et al, 1986b;Rodgers, 1965), uveitis (Pinheiro, 1990(Pinheiro, , 1995Mochizuki et al, 1992) and infective dermatitis . HTLV-I has also been linked to cases of polymyositis (Inose et al, 1992;Beilke et al, 1996), synovitis (Sowa, 1992), thyroiditis (Kawai et al, 1992) and bronchioalveolar pneumonitis (Kimura, 1992), although definitive epidemiologic proof of HTLV-I association is lacking.…”

Section: Clinical Epidemiology Of Htlv-i-associated Diseasesmentioning

confidence: 99%

Global epidemiology of HTLV-I infection and associated diseases

et al. 2005

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“…HTLV-1 associated uveitis (HAU) has since been reported in Brazil and Martinique [59,130]. HAU occurs in patients with other HTLV-1 associated inflammatory conditions such as HAM/TSP [131] and Graves' disease/autoimmune thyroiditis [132][133][134].…”

Section: Htlv-1 Associated Uveitismentioning

confidence: 99%

Inflammatory manifestations of HTLV-1 and their therapeutic options

Martin

Taylor

Jacobson

2014

Expert Review of Clinical Immunology

103

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Human T lymphotropic virus type 1 (HTLV-1) is one of the most intriguing retroviruses infecting humans. Most commonly, infection remains undetected, since it does not cause obvious harm, yet in 4-9% of patients, this infection can be devastating, causing adult T-cell leukemia/lymphoma and/or HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). This review concentrates on all inflammatory aspects of HTLV-1 infection: HAM/TSP, HTLV-1 associated uveitis, HTLV-1 associated conjunctivitis, sicca syndrome and interstitial keratitis, HTLV-1 associated Sjö gren's syndrome, Hashimoto's thyroiditis and Graves' disease, HTLV-1 associated pulmonary disease, infective dermatitis associated with HTLV-1, HTLV-1 associated inflammatory myositis and HTLV-1 associated arthritis. With the exception of HAM/TSP treatment, studies of these conditions are sparse and even for HAM/TSP, the level of evidence is limited. While control or elimination of infection remains a goal, most therapy beyond symptomatic management is directed at the immune response to HTLV-1.

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HTLV-I/II seroprevalence in 55 Brazilian patients with idiopathic uveitis

Cited by 8 publications

References 4 publications

Human T-Cell Lymphotropic Virus Type 1 Infection and Ocular Manifestations in São Paulo, Brazil

Human T-Cell Lymphotropic Virus Type 1 Infection and Ocular Manifestations in São Paulo, Brazil

Global epidemiology of HTLV-I infection and associated diseases

Inflammatory manifestations of HTLV-1 and their therapeutic options

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