HPLC-UV-ESI-MS phyto-analysis and biological activities of Rhanterium adpressum extracts (Asteraceae) from southern Algeria

Boussoussa, Hadjer; Benabed, Khadidja Houda; Khacheba, Ihcen; Surmont, Pieter; Lynen, Frédéric; Yousfi, Mohamed

doi:10.1016/j.sajb.2022.08.039

Cited by 3 publications

(1 citation statement)

References 23 publications

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“…A presence of multiple polymethoxylated flavonols, derivatives of quercetin and quercetagetin, in the plants of the subtribe has been also frequently reported. Inula helenium; I. inuloides [38] [39] [40] Chrysin 5-methyl ether (CID: 5490127) 7-Hydroxy-5methoxyflavone Rhanterium adpressum [41] (CID: 5282073) 7,4'-Dihydroxyflavone Inula salsoloides [42] Galangin (CID: 5281616) 3,5,7-Trihydroxyflavone Limbarda crithmoides [43] Apigenin Vicoa divaricata; Vicoa indica [46] [64]…”

Section: Flavonoidsmentioning

confidence: 99%

Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

Malarz,

Michalska,

Stojakowska

2024

Preprint

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Polyphenols are ubiquitous plant metabolites that demonstrate biological activities essential to the plant-environment interactions. They are of interest to plant food consumers, as well as to the food, pharmaceutical and cosmetic industry. The class of the plant metabolites comprises both widespread (chlorogenic acids, luteolin, quercetin) and unique compounds of diverse chemical structures but of the common biosynthetic origin. Polyphenols, next to sesquiterpenoids are regarded as the major class of the Inuleae-Inulinae metabolites responsible for the pharmacological activity of medicinal plants from the subtribe (Blumea spp., Dittrichia spp., Inula spp., Pulicaria spp. and others). Recent decades have brought a rapid development of molecular and analytical techniques which resulted in better understanding of the taxonomic relationships within the Inuleae tribe and in a plethora of data concerning the chemical constituents of the Inuleae-Inulinae. The current taxonomical classification has introduced changes in the well-established botanical names and rearranged the genera based on molecular plant genetic studies. The newly created chemical data together with the earlier phytochemical studies may provide some complementary information on biochemical relationships within the subtribe. Moreover, they may at least partly explain pharmacological activities of the plant preparations traditionally used in therapy. The current review aimed to systematize the knowledge on the polyphenols of the Inulae-Inulinae.

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Section: Flavonoidsmentioning

confidence: 99%

Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

Malarz,

Michalska,

Stojakowska

2024

Preprint

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In‐Vitro Antimicrobial, Antidiabetic and Anticancer Activities of Calyptocarpus Vialis Extract and its Integration with Computational Studies

Bachhar,

Joshi,

Shekher Mishra

et al. 2024

ChemistrySelect

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Calyptocarpus vialis (C. vialis), a plant of Asteraceae family exhibits nutritional value, antioxidant properties and has potential for various other biomedical applications. The present study is focused to assess the antimicrobial, antidiabetic, and anticancer potential of C. vialis extract and its integration with computational studies. The antimicrobial activity is performed against the Staphylococcus aureus (S. aureus), Bacillus subtilis (B. subtilis) pseudomonas aeruginosa (P. aeruginosa), Escherichia coli (E. coli) bacteria and Saccharomyces cerevisiae (S. cerevisiae), Candida albicans (C. albicans) fungi using disc diffusion method. Maximum Zone of Inhibition (ZOI) of 37±3.2 and 35±2.9 mm is obtained for S. aureus and B. subtilis respectively, whereas ZOI of 39±2.8 mm is obtained against C. albicans at dose of 500 μg/mL. The extract shows strong α‐amylase inhibition activity with IC50 ~46.8±0.81 μg/mL inferring about its antidiabetic potential. Anticancer activity of C. vialis extract is checked against HCT‐116 and DU‐145 cell lines using 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium‐bromide (MTT) assay, which shows excellent anticancer activity with IC50 value of 38.09±0.65 μg/ml and 36.34±1.05 μg/ml respectively. The obtained results are further verified using computational studies considering interaction among phytochemicals and selected targets. Extract is found potent for biological activities and promising candidate for development of new drugs.

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Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

Malarz,

Michalska,

Stojakowska

2024

Molecules

View full text Add to dashboard Cite

Polyphenols are ubiquitous plant metabolites that demonstrate biological activities essential to plant–environment interactions. They are of interest to plant food consumers, as well as to the food, pharmaceutical and cosmetic industry. The class of the plant metabolites comprises both widespread (chlorogenic acids, luteolin, quercetin) and unique compounds of diverse chemical structures but of the common biosynthetic origin. Polyphenols next to sesquiterpenoids are regarded as the major class of the Inuleae-Inulinae metabolites responsible for the pharmacological activity of medicinal plants from the subtribe (Blumea spp., Dittrichia spp., Inula spp., Pulicaria spp. and others). Recent decades have brought a rapid development of molecular and analytical techniques which resulted in better understanding of the taxonomic relationships within the Inuleae tribe and in a plethora of data concerning the chemical constituents of the Inuleae-Inulinae. The current taxonomical classification has introduced changes in the well-established botanical names and rearranged the genera based on molecular plant genetic studies. The newly created chemical data together with the earlier phytochemical studies may provide some complementary information on biochemical relationships within the subtribe. Moreover, they may at least partly explain pharmacological activities of the plant preparations traditionally used in therapy. The current review aimed to systematize the knowledge on the polyphenols of the Inulae-Inulinae.

show abstract

HPLC-UV-ESI-MS phyto-analysis and biological activities of Rhanterium adpressum extracts (Asteraceae) from southern Algeria

Cited by 3 publications

References 23 publications

Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

In‐Vitro Antimicrobial, Antidiabetic and Anticancer Activities of Calyptocarpus Vialis Extract and its Integration with Computational Studies

Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

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