HPLC Profiling and Antioxidant Properties of the Ethanol Extract of Hibiscus tiliaceus Leaf Available in Bangladesh

Hossain, Hemayet; Akbar, Proity Nayeeb; Rahman, Shaikh Mizanur; Yeasmin, Sabina; Khan, Tanzir Ahmed; Rahman, Md. Mahfuzur; Jahan, Israt

doi:10.9734/ejmp/2015/14720

Cited by 5 publications

(1 citation statement)

References 19 publications

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“…Kandungan senyawa aktif dalam daun waru adalah polifenol, flavonoid, terpenoid, steroid dan glikosida (Samsudin et al, 2019). Penelitian lain menunjukkan daun waru mengandung katekin, rutin dan kuersetin yang merupakan golongan senyawa flavonoid (Hossain et al, 2015). Berbagai penelitian menunjukkan peran flavonoid sebagai agen yang dapat menurunkan resiko terjadinya kanker maupun sebagai agen kemoterapi (Batra & Sharma, 2013).…”

Section: Hasil Dan Pembahasanunclassified

AKTIVITAS SITOTOKSIK DAN PENGHAMBATAN MIGRASI SEL KANKER 4T1 DARI EKSTRAK DAUN WARU (Hibiscus tiliaceus Linn.)

Hidayati

Safitri²,

Alviani³

et al. 2022

J. Tumbuhan Obat Indonesia

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Kanker payudara merupakan jenis penyakit kanker dengan prevalensi tertinggi di Indonesia. Kegagalan dalam terapi kanker akibat resistensi sel telah mendorong upaya pengembangan obat anti kanker, terutama dari bahan alam. Beberapa penelitian menunjukkan daun waru memiliki aktivitas sitotoksik. Penelitian ini bertujuan untuk mengetahui aktivitas sitotoksik dan penghambatan migrasi sel oleh ekstrak daun waru terhadap sel kanker payudara 4T1. Ekstrak daun waru (Hibiscus tiliaceus Linn.) diperoleh dengan metode maserasi. Uji sitotoksisitas ekstrak daun waru dilakukan dengan MTT assay. Uji penghambatan migrasi sel dilakukan dengan metode scratch wound healing. Hasil penelitian menunjukkan nilai IC50 pada sel 4T1 sebesar 892,4 µg/mL. Ekstrak daun waru konsentrasi 892 μg/mL, 446 dan 223 µg/mL mampu menghambat migrasi sel kanker payudara 4T1 berdasarkan persentase penutupan sel pada jam ke 18, 24 dan 42. Dengan demikian, ekstrak daun waru berpotensi untuk dikembangkan lebih lanjut sebagai agen antimigrasi pada sel kanker payudara 4T1.

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Section: Hasil Dan Pembahasanunclassified

AKTIVITAS SITOTOKSIK DAN PENGHAMBATAN MIGRASI SEL KANKER 4T1 DARI EKSTRAK DAUN WARU (Hibiscus tiliaceus Linn.)

Hidayati

Safitri²,

Alviani³

et al. 2022

J. Tumbuhan Obat Indonesia

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The complete chloroplast genome sequence of the mangrove associate speciesTalipariti tiliaceum

Qiu¹,

Zhu

et al. 2021

Mitochondrial DNA Part B

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Talipariti tiliaceum is an evergreen mangrove associate species distributed throughout the world. In this study, the complete chloroplast genome sequence of T. tiliaceum was assembled and characterized using high-throughput sequencing data. The chloroplast genome was found to be 161 766 bp in length, consisting of large single-copy (LSC) and small single-copy (SSC) regions of 89 273 and 19 551 bp, respectively, which were separated by a pair of 26 471 bp inverted repeat (IR) regions. The genome contained 129 genes, including 84 protein-coding genes, 37 tRNA genes, and 8 rRNA genes. A phylogenetic tree including 66 chloroplast genomes from various species revealed that T. tiliaceum was most related to T. hamabo of the same genus.

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A current perspective on antibacterial and antibiofilm properties of waru (Hibiscus tiliaceus L.)

Husnah

Suhartono

Ismail

2021

IOP Conf. Ser.: Earth Environ. Sci.

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During the long course of evolution, disease-causing pathogenic bacteria have developed a variety of virulence mechanisms that help them establish and maintain infections. Among these mechanisms are the production of biofilm protecting the bacteria from undesirable environmental conditions and contributing to the development of new multi-drug-resistance bacterial strains. Hence, biofilm has become an attracted target for the development of a novel strategy in fighting against biofilm-forming pathogens. There has been much work to look for novel antibacterial and antibiofilm agents, including the use of plant-derived materials. Hibiscus tiliaceus is one of the widely known medicinal plant with antibacterial and antibiofilm properties. This review focuses on antibacterial and antibiofilm properties of H. tiliaceus as well as the major phytochemical constituents that might contribute to these activities.

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HPLC Profiling and Antioxidant Properties of the Ethanol Extract of Hibiscus tiliaceus Leaf Available in Bangladesh

Cited by 5 publications

References 19 publications

AKTIVITAS SITOTOKSIK DAN PENGHAMBATAN MIGRASI SEL KANKER 4T1 DARI EKSTRAK DAUN WARU (Hibiscus tiliaceus Linn.)

AKTIVITAS SITOTOKSIK DAN PENGHAMBATAN MIGRASI SEL KANKER 4T1 DARI EKSTRAK DAUN WARU (Hibiscus tiliaceus Linn.)

The complete chloroplast genome sequence of the mangrove associate speciesTalipariti tiliaceum

A current perspective on antibacterial and antibiofilm properties of waru (Hibiscus tiliaceus L.)

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