2007
DOI: 10.1007/s11418-007-0154-7
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HPLC analysis of coumarins in Turkish Seseli species (Umbelliferae)

Abstract: The n-hexane extracts of aerial and underground parts of three Seseli species, S. gummiferum subsp. corymbosum, S. resinosum, and S. hartvigii growing in Turkey were investigated concerning the presence of coumarins by normal-phase HPLC (high-performance liquid chromatography). In this respect, two coumarins, osthol (1) and corymbocoumarin (2) [(-)-(3¢S, 4¢S)-3¢-acetoxy-4¢-isovaleryloxy-3¢, 4¢-dihydroseselin] isolated from aerial parts of S. gummiferum subsp. corymbosum, were used as standard samples. The amou… Show more

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Cited by 18 publications
(10 citation statements)
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“…As reported by Tosun et al [14], Seseli gummiferum and also other species of the genus Seseli could contain pyranocoumarins. The mild extraction conditions (P ¼ 90 bar, T ¼ 50 C, ¼ 0.287 g cm À3 ) and a two-stages separation, adopted in our study, chosen to obtain an high recovery of the volatile oil, allowed us to obtain an extract essentially devoid of undesired compounds of higher molecular weight as coumarins, psoralens, dyes, long-chain hydrocarbons and FAMEs.…”
Section: Resultsmentioning
confidence: 51%
See 1 more Smart Citation
“…As reported by Tosun et al [14], Seseli gummiferum and also other species of the genus Seseli could contain pyranocoumarins. The mild extraction conditions (P ¼ 90 bar, T ¼ 50 C, ¼ 0.287 g cm À3 ) and a two-stages separation, adopted in our study, chosen to obtain an high recovery of the volatile oil, allowed us to obtain an extract essentially devoid of undesired compounds of higher molecular weight as coumarins, psoralens, dyes, long-chain hydrocarbons and FAMEs.…”
Section: Resultsmentioning
confidence: 51%
“…Habibi et al [12] reported the chemical composition of hydrodistilled oil of S. tortuosum from Iran: -pinene, -phellandrene and sabinene were the main constituents. Tosun et al [13] reported the composition of the essential oils from Seseli species (gummiferum subsp. gummiferum and subsp.…”
Section: Resultsmentioning
confidence: 99%
“…These include simultaneous determination of five furocoumarins in Angelica dahurica by LC-UV [19,20], qualitative determination of the major coumarins in Zushima and simultaneous determination of coumarin derivatives in Dendrobium thyrsiflorum by LC-DAD-ESI-MS [21,22], chromatographic characterization of furocoumarins by LC-DAD-ESI-MS n in the roots of Angelica dahurica [23], LC-MS and MECC analysis of coumarins [24]. LC-DAD-ESI-MS has been proven to be a powerful method for the rapid identification and determination of the ingredients in traditional Chinese medicine or botanic extracts.…”
Section: Introductionmentioning
confidence: 99%
“…On the basis of previously conducted chemical studies, it is known that Seseli species are a source of coumarins, sesquiterpenes, and phenyl propanoides. 5-9 Previous analyses of the essential oils from various Seseli species demonstrated that the main components are quite different from species to species: sabinene, α-pinene, and β-phellandrene in S. globiferum aerial parts 10 ; α-pinene in S. rigidum Waldst. & Kit.…”
mentioning
confidence: 99%