How to predict forced vital capacity after living-donor lobar-lung transplantation

Native Lung-sparing Lobar Transplantation for Pulmonary Emphysema

“…7 Hence, large adult patients are believed to be poor candidates for LDLLT; NLSLT provides an opportunity for lung transplantation in such patients. As we previously reported that overall survival in patients having LDLLT reached 93.6%, 2 NLSLT is also expected to provide a survival benefit to patients.…”

Favorable outcomes after living-donor lobar lung transplantation in ventilator-dependent patients

“…We previously proposed a size-matching formula to estimate the graft forced vital capacity (FVC) based on the donor's measured FVC and the number of pulmonary segments implanted. 8 When the total FVC of the two grafts was greater than 45%-50% of the predicted FVC of the recipient, we accepted the size disparity, regardless of the recipient's diagnosis.…”

“…Postoperative immunosuppression consisted of triple-drug therapy with cyclosporine or tacrolimus, azathioprine, or mycophenolate mofetil (MMF), and corticosteroids. 8 Induction cytolytic therapy was not used. We gave patients with infectious lung diseases, pediatric patients, and patients already receiving steroids a combination of cyclosporine, azathioprine, and steroids; and all others a combination of tacrolimus, MMF, and steroids.…”

Living Related Lung Transplantation

“…It allows us to perform more precise functional matching in LDLLT. For "functional size matching", we rely on graft FVC (4,21). We have made a formula for estimating the graft FVC based on the donor's measured FVC and the number of pulmonary segments implanted.…”