How much does it cost to preserve a larynx?

León, Xavier; Quer, Miquel; Orús, César; López‐Pousa, Antonio; Pericay, C.; Vega, Manuel de

doi:10.1007/pl00007513

Cited by 21 publications

(7 citation statements)

References 14 publications

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“…According to the decision-analysis model in this study, total laryngectomy with postoperative radiotherapy yields lower direct medical costs by $2914 per patient com-(REPRINTED) ARCH OTOLARYNGOL HEAD NECK SURG/ VOL 131, JAN 2005 pared with an organ preservation protocol in the management of advanced laryngeal cancer. This finding agrees with that reported by Leon and colleagues, 33 who retrospectively reviewed medical records from 96 patients from Spain with stage III glottic tumors and found surgery to be less expensive than organ preservation by €600.…”

Section: Commentsupporting

confidence: 92%

Cost Comparison of Surgery vs Organ Preservation for Laryngeal Cancer

Davis

Schwartz

Veenstra

et al. 2005

Arch Otolaryngol Head Neck Surg

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Objective: To perform a cost minimization analysis of total laryngectomy with postoperative radiotherapy vs induction chemotherapy with subsequent radiotherapy in patients with advanced (stage III or IV) squamous cell carcinoma of the larynx.Design: Decision-analysis model using data from peerreviewed trials, case series, meta-analyses, and Medicare diagnosis related group reimbursement rates. Setting and Patients:A hypothetical cohort of patients with stage III or IV laryngeal cancer. The perspective is that of a health care payer. Interventions:The hypothetical patient cohort could receive (1) surgery (total laryngectomy) with postoperative radiotherapy or (2) induction chemotherapy (fluorouracil and cisplatin) with radiotherapy followed by salvage surgery for patients failing to respond to chemotherapy.Main Outcome Measure: Overall difference in direct medical costs in 2003 US dollars between the 2 treatment arms from initiation to completion of treatment. Results:In the baseline analysis, the direct medical costs for the surgical arm were $30138 per patient. For the organ preservation arm, the direct medical costs were $33052 per patient. The finding that the surgical arm costs were lower was robust to all sensitivity analyses except for the extreme low estimate for the cost of chemotherapy. Conclusions:Our results suggest that total laryngectomy with postoperative radiotherapy costs nearly $3000 less than organ preservation treatment for advanced laryngeal cancer. Given that survival appears equivalent between the 2 modalities, cost consideration and patient preference may be important factors in decision making for the treatment of advanced laryngeal cancer.

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Section: Commentsupporting

confidence: 92%

Cost Comparison of Surgery vs Organ Preservation for Laryngeal Cancer

Davis

Schwartz

Veenstra

et al. 2005

Arch Otolaryngol Head Neck Surg

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“…Although some trials have shown an improvement in some components of quality of life (8, 30) many others have described equivalent results (31)(32)(33)(34). Furthermore, cost consideration may be an important factor in decision making for the treatment of advanced laryngeal cancer (35,36).…”

Section: Discussionmentioning

confidence: 95%

Organ Preservation With Concurrent Chemoradiation for Advanced Laryngeal Cancer: Are We Succeeding?

Lambert

Fortin

Soulières

et al. 2010

International Journal of Radiation Oncology*Biology*Physics

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“…Leon et al [34] compared the costs of total laryngectomy to induction chemotherapy.The average cost per laryngectomized patient with or without radiotherapy was €5,853 (2001 €6,002) while the average cost for those patients treated with induction chemotherapy was €6,452 (€6,616). Among patients who received induction chemotherapy 46% (16 of 35) did not have a laryngectomy.…”

Section: Cost-comparison Analyses Across Treatmentsmentioning

confidence: 99%

Economic burden of head and neck cancer

Lee

Turini

Botteman

et al. 2004

The European Journal of Health Economics

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This literature review presents the economics of head and neck cancer (HNC), the world's sixth most common neoplasm. HNC economics is complicated by the involvement of multiple body sites, multiple medical specialties, and multiple treatment modalities. Economic analyses of HNC published in English between 1990 and 2002 were identified from electronic data sources. Additional studies were identified manually from bibliographies of retrieved articles. Study characteristics and findings were analyzed. We identified 51 studies that reported original cost data. Most were cost-identification or cost-comparison studies; only one evaluated cost-effectiveness. Few assessed the overall economic burden of HNC or cost effectiveness of current treatments, thus making appropriate comparisons impossible. Systematic measurement of the cost of HNC and its treatment in existing practice settings would be valuable. Inclusion of economic components in clinical trials and the conduct of retrospective or prospective observational studies, such as patient registries, would yield important new information.

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How much does it cost to preserve a larynx?

Cited by 21 publications

References 14 publications

Cost Comparison of Surgery vs Organ Preservation for Laryngeal Cancer

Cost Comparison of Surgery vs Organ Preservation for Laryngeal Cancer

Organ Preservation With Concurrent Chemoradiation for Advanced Laryngeal Cancer: Are We Succeeding?

Economic burden of head and neck cancer

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