How functional foods play critical roles in human health

Pang, Guangchang; Xie, Junbo; Qing-sen, Chen; Zhi-he, HU

doi:10.1016/j.fshw.2012.10.001

Cited by 95 publications

(64 citation statements)

References 343 publications

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“…These ingredients might help the bacteria to slightly but not totally resist the antibacterial effect of the prepared mix. Here, we can clarify that, Breast feeding lactation can provide babies with almost all nutritional requirements in addition to beneficial components as IgG antibodies (Pang et al 2012). Regarding this concept, mothers can act as a mediator to transfer the beneficial constituents of medicinal plants to babies through their milk.…”

Section: Determination Of Phenolic Compounds and Flavonoids Of Mix2 Bmentioning

confidence: 95%

Advanced trends in controlling Helicobacter pylori infections using functional and therapeutically supplements in baby milk

et al. 2015

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Helicobacter pylori is a common human pathogen infecting about 30 % of children and 60 % of adults worldwide. It is responsible for diseases such as gastritis, peptic ulcer and gastric cancer. H. pylori treatment based on antibiotics with proton pump inhibitor, but therapy failure is shown to be higher than 20 % and is essentially due to an increasing in prevalence of antibiotic-resistant bacteria, which has led to the search for alternative therapies. In this study, we discuss the usage of natural extracts mixture as alternative or complementary agents in controlling H. pylori infection so here, we focused on the plant extracts of (Cloves, Pepper, Cumin, Sage, Pomegranate peel, Ginger, Myrrh and Licorice). To that end, Phytochemical constituents detection like Tannins, Glycosides, Alkaloids, Flavonoids, Terpenoids, Saponins, Phenolic compounds, Reducing sugars, Volatile oils, Amino acids and Proteins was demonstrated. Each plant extract was examined individually or in combination for its antimicrobial activity against H. pylori. Out of the used extracts, four mixes were prepared and tested against H. pylori. The antibacterial activities of the four mixes, represented by the diameter of inhibition clear zone, recorded 21, 39, 23 and 28 mm. The most potent mix (mix2) was chosen and mixed with baby milk as a new combination for H. pylori infections treatment in babies.

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Section: Determination Of Phenolic Compounds and Flavonoids Of Mix2 Bmentioning

confidence: 95%

Advanced trends in controlling Helicobacter pylori infections using functional and therapeutically supplements in baby milk

et al. 2015

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“…Probiotics were selected based on antioxidative and anti-inflammatory effects, which have been reported in the past studies (Fijan. 2014, Hamaji et al 2007, Messaoudi et al 2011, Pang et al 2012). Probiotics powder was colorless and odorless; at first, probiotics are inactive in water due to their special formulation, which includes a carrier compound that bonds to probiotics and allows probiotics activation in gut.…”

Section: Probiotics Preparationmentioning

confidence: 99%

Probiotics improve insulin resistance status in an experimental model of Alzheimer’s disease

Azm

Djazayery

Safa

et al. 2017

Med. J. Islam. Republic Iran

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↑What is "already known" in this topic: Studies have shown that probiotics can be a nutritional approach to improve metabolic markers such as FBS and lipid profile in patients with diabetes.→What this article adds: Disruption of insulin signaling cascade and insulin resistance can induce AD that causes systemic alterations in serum insulin, FBS levels, and lipid profile; however, probiotics can improve these markers. Probiotics improve insulin AbstractBackground: Nowadays, Alzheimer's disease (AD) is considered as Type 3 diabetes in which insulin resistance is the common cause of both diseases. Disruption of insulin signaling cascade and insulin resistance can induce AD; and central insulin resistance causes systemic alterations in serum insulin, FBS levels, and lipid profile. Studies have shown that probiotics (Lactobacillus and Bifidobacterium species) can be used as a nutritional approach to improve these metabolic changes. We assessed the probiotic effect (4 species of Lactobacillus and Bifidobacterium) on insulin resistance biomarkers in an experimental model of AD.Methods: A total of 60 rats were divided into 5 groups: (1) a control group without surgical and dietary intervention; (2) a controlprobiotics group receiving probiotics for 8 weeks, but not receiving any surgical intervention; (3) a group receiving a sham operation in which PBS was injected intrahippocampus but without dietary intervention; (4) an Alzheimer group for which Amyloid-ß (Aß) 1-42 was injected intrahippocampus but without dietary intervention; (5) and an Alzheimer-probiotics group for which Aß1-42 was injected intrahippocampus and given 2g probiotics for 8 weeks. The FBS levels and lipid profile were measured by a calorimetric method, insulin levels were detected by an ELISA kit, and HOMA-IR was calculated using a formula. ANOVA (one way analysis of variance followed by Bonferroni comparisons post hoc) was used to compare all the variables between groups.Results: Serum glucose, insulin levels, and HOMA-IR index increased in the Alzheimer group compared to the control (p<0.001), while probiotics decreased only insulin level and HOMA-IR index in AP group compared to Alzheimer group (p<0.001). Also, TG levels increased in the Alzheimer group (p<0.001), but no significant difference was detected between Alzheimer and Alzheimerprobiotics group.Conclusion: It seems that probiotics play an effective role in controlling glycemic status of Alzheimer's disease.

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“…Probiotics are usually defined as microbial food supplements that have beneficial effects on consumers (Pang, Xie, Chen, & Hu, 2012).…”

Section: Food In Human Healthmentioning

confidence: 99%

Survival of Lactobacillus rhamnosus GG during Simulated Gastrointestinal Conditions Depending on Food Matrix

Karu

Sumeri

2016

JFR

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When developing new probiotic foods, their protective properties in maintaining viability of probiotics under gastrointestinal conditions should be evaluated. In the current study, human upper gastrointestinal tract simulator (GITS) was used to compare the effect of different food matrixes on the survival of Lactobacillus rhamnosus GG (LGG). pH-auxostat was chosen for the cultivation of LGG cells to obtain culture samples in the same physiological state at maximum growth rate for the GITS experiments. The LGG culture was centrifuged and fast frozen in liquid nitrogen in various liquid food matrixes (commercial UHT milk, soymilk, apple juice, titrated apple juice, whey protein powder drink and M.R.S. Broth as reference) and stored at -40 0 C. During 3-month storage, reduction of viability was significant only for apple juice. In the GITS experiments, bile had a greater negative impact on LGG than acid conditions, also the effect of food matrix was noted -in the case of milk, soymilk and whey protein powder drink only the highest concentration of bile (0.4%) caused a significant drop in the viability of bacteria when compared to apple juice. To maximize the health benefits of foodstuffs, it should be taken into account that the survival of probiotics during fast freezing, storage and gastrointestinal passage is dependent on the food matrix.

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How functional foods play critical roles in human health

Cited by 95 publications

References 343 publications

Advanced trends in controlling Helicobacter pylori infections using functional and therapeutically supplements in baby milk

Advanced trends in controlling Helicobacter pylori infections using functional and therapeutically supplements in baby milk

Probiotics improve insulin resistance status in an experimental model of Alzheimer’s disease

Survival of Lactobacillus rhamnosus GG during Simulated Gastrointestinal Conditions Depending on Food Matrix

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