How clean is clean enough? An observational pilot study to assess central sterilization processing efficacy with adenosine triphosphate levels

Fitts, Lauren N.; Yegge, Jeanne; Goris, Ashleigh J.; Vinson, Sara; Dubberke, Erik R.

doi:10.1016/j.ajic.2019.08.006

Cited by 4 publications

(1 citation statement)

References 5 publications

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“…With the routine cleaning and monitoring of surgical instruments, the pass/fail threshold for instruments cleaned by an automated washer-disinfector is: Pass ⩽ 150 RLU, Fail ⩾ 151 RLU. The pass/fail threshold is based on clinical studies and the vendors’ validation studies that that level of cleanness can routinely be achieved after the washer-disinfector’s thermal disinfection cycle (Bommarito et al, 2011; Fitts et al, 2020).…”

Section: Resultsmentioning

confidence: 99%

Effective disinfecting of protective devices used in the course of treating SARS-CoV2–positive patients

Tan

Feng

Liang

et al. 2021

Journal of Infection Prevention

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Background: Powered Air-Purifying Respirator (PAPR) was widely used in Sengkang General Hospital (SKH) during the SARS-CoV-2 outbreak. Ensuring a sustained supply of clean and reusable PAPR masks for frontline medical team is an immediate challenge. The Central Sterile Supplies Unit (CSSU) adopts existing disinfection methods and technology for the reprocessing of reusable personal protective equipment (PPE) such as PAPR masks and goggles. Objective: To determine an effective disinfecting method for protective devices used in the course of treating SARS-CoV2–positive patients. Method: A comparison on surface disinfection and modified thermal disinfection outcome was conducted on 30 PAPR masks through detecting the presence of adenosine triphosphate (ATP) by swab following both disinfecting methods. Results: The modified thermal cycles emerged as the recommended disinfection method. Discussion: The outcome of this study has enhanced understanding on the risk imposed on frontline healthcare personnel who perform surface disinfecting on masks for reuse during the work shift. Leveraging on the current expertise from existing instrument logistics, CSSU takes charge of the processing and stock management of SKH’s PAPR masks. An additional workflow is needed to establish reprocessing methods for other reusable PPEs such as face shields or overalls.

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Section: Resultsmentioning

confidence: 99%

Effective disinfecting of protective devices used in the course of treating SARS-CoV2–positive patients

Tan

Feng

Liang

et al. 2021

Journal of Infection Prevention

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Evaluation of cleaning process efficacy of instruments for robotic surgery using the adenosine triphosphate test

Dolci

Lobo

Nunes

et al. 2023

Surgery

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Monitoring the Cleanliness of Reusable Surgical Instruments in Central Sterile Supply Department by Adenosine Triphosphate Method

Cai

et al. 2021

Journal of AOAC INTERNATIONAL

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Background Cleaning is very important in reusable surgical instruments (RSI) reprocessing. Adenosine triphosphate (ATP) method is widely used for cleanliness assessing while few studies focused on using this method on RSIs. Objective To assess the effectiveness of ATP Bioluminescence Assay for monitoring the cleanliness of RSIs. Methods The study conducted in three central sterile supply departments (CSSD) from 2015 to 2020, surgical scissors, haemostatic forceps, and other non-lumen instruments after cleaning were sampled. Each instrument was swabbed in a uniform manner on the surface including hinged joints and teeth, the amount of ATP (amol) was calculated. Results A total of 871 RSIs after cleaning were tested, the mean ATP lg (amol) was 2.829 ± 0.539 and the qualified rate was 80.57%. Washer-disinfector cleaning was more efficiency than manual cleaning, the mean ATP lg (amol) were 2.776 ± 0.513 and 2.948 ± 0.575, respectively; the qualified rates were 84.97% and 70.59%, respectively. The qualified rate was decreased with the time of instruments after cleaning exploring to environment increased (P trend = 0.044). Conclusion ATP level are stable and repeatable for continuous monitoring the cleanliness of RSIs, it is a rapid and viable method for assessing the cleanliness of RSIs. Washer-disinfector cleaning is recommended and cleaned instruments should go on packing for sterilization in time. Highlights - ATP method is viable for assessing the cleanliness of reusable surgical instruments in CSSDs. - Reusable surgical instruments suggested washer-disinfector cleaning and should go on packing for sterilization in time.

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How clean is clean enough? An observational pilot study to assess central sterilization processing efficacy with adenosine triphosphate levels

Cited by 4 publications

References 5 publications

Effective disinfecting of protective devices used in the course of treating SARS-CoV2–positive patients

Effective disinfecting of protective devices used in the course of treating SARS-CoV2–positive patients

Evaluation of cleaning process efficacy of instruments for robotic surgery using the adenosine triphosphate test

Monitoring the Cleanliness of Reusable Surgical Instruments in Central Sterile Supply Department by Adenosine Triphosphate Method

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