2017
DOI: 10.1590/s1806-37562017000100001
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How can anemia negatively influence gas exchange?

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Cited by 5 publications
(8 citation statements)
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“…Despite the relatively small sample size and the lack of metabolic parameters of SCT carrier mice, we believe that our findings may pave the ground for further insights aimed at clarifying the molecular regulation of the endothelial response in SCT carriers. Furthermore, our results underpin the utility of the SCT carrier animal model for the study of the mechanisms by which vascular complications may occur in previously asymptomatic SCT carriers [ 11 , 12 , 13 , 14 , 15 ]. In this context, it should be considered that combined light microscopy and TEM analysis should be recommended to detect relevant microanatomical alterations.…”
Section: Discussionmentioning
confidence: 79%
See 1 more Smart Citation
“…Despite the relatively small sample size and the lack of metabolic parameters of SCT carrier mice, we believe that our findings may pave the ground for further insights aimed at clarifying the molecular regulation of the endothelial response in SCT carriers. Furthermore, our results underpin the utility of the SCT carrier animal model for the study of the mechanisms by which vascular complications may occur in previously asymptomatic SCT carriers [ 11 , 12 , 13 , 14 , 15 ]. In this context, it should be considered that combined light microscopy and TEM analysis should be recommended to detect relevant microanatomical alterations.…”
Section: Discussionmentioning
confidence: 79%
“…On the other hand, heterozygous subjects (HBB A/S carriers of sickle cell trait—SCT) are virtually considered healthy subjects [ 8 , 9 , 10 ]. However, new clinical evidence is leading to a reconsideration of the importance and frequency of some complications observed in SCT carriers: exertion-related injury, chronic kidney disease (CKD), renal medullary carcinoma, thrombo-embolic diseases, and arteriopathies [ 11 , 12 , 13 , 14 , 15 ].…”
Section: Introductionmentioning
confidence: 99%
“…A presença de hemoglobinopatias fora descartada pela presença de hemograma normal prévio (realizado no primeiro atendimento). A possibilidade de shunts cardíacos e pulmonares e as malformações arteriovenosas pulmonares também fora considerada Brazilian Journal of Health Review, Curitiba, v. 7, n. 3, p. 01-10, may/jun., 2024 improvável por sua história natural não ser condizente com a história clínica da paciente (Ramos, 2017).…”
Section: Relato Do Casounclassified
“…Oxygen saturation (SaO 2 ) is the representative of percentage of oxygen occupied on the binding sites on haemoglobin [1]. Adequate oxygen delivery to organs depends on effective oxygen transport to the tissue mitochondria, a critical task that is performed by haemoglobin and this is greatly reduced in anaemic state [2]. Reduced oxygen saturation results in inadequate tissue supply, particularly when oxygen demand is increased, as occurs during exercise [3].…”
Section: Introductionmentioning
confidence: 99%