Hot off the press

Laxiflorol A, the first example of 7,8:15,16-di-seco-15-nor-21-homo-ent-kauranoid from Isodon eriocalyx var. laxiflora

“…2 Ent-kaurane-type diterpenoids represent one of the most excellent examples of natural products with diverse structural scaffolds and important pharmaceutical activities. 2,3 Among these compounds in our library, many unique structures, including ternifolide A, 4 neoadenoloside A, 4 neolaxiorin A, 5 nervonin A, 6 maoecrystal Z, 7 maoecrystal V, 8 xindongnin M, 9 neoangustifolin 10 and epinodosino 10 , have been reported by Natural Product Reports as hot off the press. Some compounds, such as oridonin, 11 eriocalyxin B, 12 adenanthin, 3a pharicin B, 3b and other compounds, have brought great attention to their potential antitumor application.…”