Hot and Cold Natures and Some Parameters of Neuroendocrine and Immune Systems in Traditional Iranian Medicine: A Preliminary Study

Shahabi, Shahram; Hassan, Zuhair Muhammad; Mahdavi, Mehdi; Dezfouli, Mahya; Rahvar, Monireh Torabi; Naseri, Mohsen; Jazani, Nima Hosseni; Khalkhali, Hamidreza

doi:10.1089/acm.2007.0693

Cited by 61 publications

(33 citation statements)

References 17 publications

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“…There were no serious adverse effects in any of the 65 MS patients. [Shahabi et al, 2008]. This concept can be one of the causes (in addition to others) of differing susceptibilities to specific diseases between different people [Kaplan et al, 2001].…”

Section: Edss P For Paired-t Test *mentioning

confidence: 99%

“…This concept can be one of the causes (in addition to others) of differing susceptibilities to specific diseases between different people [Kaplan et al, 2001]. Based on TIM practitioners' view, MS is a Th1-mediated autoimmune disease is more prevalent in Cold nature persons [Shahabi et al, 2008], so consumption of Hot nature foods may be useful because they can accelerate warmth of nature and deviation toward Th2 immune responses and may lead to a reduction in disease severity [Mirzaei, 2007].…”

Section: Edss P For Paired-t Test *mentioning

confidence: 99%

“…The theory of Hot and Cold natures in people and foods finds its origin in ancient Greece, by Hippocrates (Greek physician, 460-375 BC) and Galen (199-129 BC) [Chiappelli et al, 2005;Ody, 1993;Ott, 1997]. Shahabi et al (2008) showed the people of a Hot nature had more deviation of the immune system toward T-helper (Th2) responses than the subjects of a Cold nature, and in concordance with Traditional Iranian Medicine (TIM) practitioners' view that MS which is a Th1-mediated autoimmune disease occurs in persons of a Cold nature. Thus, the consumption of Hot Nature diet by persons suffering from an autoimmune disease with a deviation toward Th1 immune responses (such as MS) might be useful, as Shahabi's results show that this diet may shift the immune system towards Th2 responses.…”

Section: Introductionmentioning

confidence: 99%

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Erythrocyte membrane fatty acids in multiple sclerosis patients and hot-nature dietary intervention with co-supplemented hemp-seed and evening-primrose oils

Rezapour-Firouzi¹,

Arefhosseini²,

Ebrahimi-Mamaghani³

et al. 2013

Afr. J. Trad. Compl. Alt. Med.

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The risk of developing multiple sclerosis (MS) is associated with increased dietary intake of saturated fatty acids. For many years it has been suspected that this disease might be associated with an imbalance between unsaturated and saturated fatty acids. We determined erythrocyte membrane fatty acids levels in Hot nature dietary intervention with co-supplemented hemp seed and evening primrose oils in multiple sclerosis patients. To determine the erythrocyte membrane fatty acids levels and correlate it with expanded disability status scale (EDSS) at baseline after 6 months intervention in MS patients by gas chromatography, in this double blind, randomized trial, 100 RRMS patients with EDSS<6 were allocated into three groups: "Group A" that received co-supplemented hemp seed and evening primrose oils with advised Hot nature diet. "Group B" received olive oil and "Group C" received the co-supplemented oils. The results showed that the mean follow-up was 180±2.9SD days (N=65, 23 M and 42 F aged 34.25±8.07 years with disease duration of 6.80±4.33 years). There was no significant difference in the study parameters at baseline. After 6 months, EDSS, Immunological parameters and the erythrocyte cell membrane with regard to specific fatty acids showed improvement in the group A and C, whereas there was worsening condition for the group B after the intervention. We concluded that Hot-nature dietary intervention with co-supplemented hemp seed and evening primrose oils caused an increase PUFAs in MS patients and improvement in the erythrocyte membrane fatty acids composition. This could be an indication of restored plasma stores, and a reflection of disease severity reduction.

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Section: Edss P For Paired-t Test *mentioning

confidence: 99%

Section: Edss P For Paired-t Test *mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Erythrocyte membrane fatty acids in multiple sclerosis patients and hot-nature dietary intervention with co-supplemented hemp-seed and evening-primrose oils

Rezapour-Firouzi¹,

Arefhosseini²,

Ebrahimi-Mamaghani³

et al. 2013

Afr. J. Trad. Compl. Alt. Med.

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“…Although there are a number of studies based on PMsuggested treatments for a variety of diseases (6)(7)(8), surveys for organizing its diagnostic criteria are rare (5).Written references of PM proposed some Mizaj assessment indices and named them the "ten criteria" (Ajnase-Ashareh) of Mizaj identifiers (9); each of them should be assessed in two fields ranging from extreme warm to extreme cold and also from extreme wet to extreme dry to define the entire body's Mizaj (10).…”

Section: Introductionmentioning

confidence: 99%

The Relationship Between Mizaj and Its Indices in Persian Medicine

Mojahedi

Alipour

Mozaffarpur

2018

Iran Red Crescent Med J

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Background: As personalized medicine is developing, similar concepts in Persian medicine need standardization. Objectives: The aim of this study was to compare the correlation of ten criteria of Mizaj assessment with Mizaj determined by experts. Methods: In this cross-sectional methodological research, 74 medical student volunteers were examined by 10 expert raters. The agreement between each ten indices and total Mizaj were assessed with the spearman correlation coefficient (r) and weighted by the kappa coefficient (wk). Results: Among ten indices, the largest agreement was observed amongst indices of psychic function, impressibility, physical function and physique with total warm or cold Mizaj and thus amongst indices of muscle and fat mass, touch and physique with total

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“…To date, differences in levels of cytokines, interleukin-4, interferon-gamma, norepinephrine, epinephrine, cortisol, and types of antibodies have been reported [9,10]. With the development of molecular approaches (high-throughput biotechniques) in the field of CAM, other molecular differences have also been described, such as the G-protein signaling pathway, T-cell proliferation, and oxidation/reduction in fatty acid metabolism [11,12,13,14].…”

Section: Introductionmentioning

confidence: 99%