Hospital-based Population of Elderly Cancer Cases in Northeastern Thailand

Wirasorn, Kosin; Suwanrungruang, Krittika; Sookprasert, Aumkhae; Limpawattana, Panita; Sirithanaphol, Wichien; Chindaprasirt, Jarin

doi:10.7314/apjcp.2016.17.2.767

Cited by 8 publications

(10 citation statements)

References 9 publications

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“…In our cohort, we found that advanced age was correlated with decreased lean muscle mass, for each 1-year age increase, appendicular muscle mass decreased 0.10 kg. Since the incidence of elderly cancer is increasing [ 23 , 24 ], evaluation of muscle mass along with geriatric assessment in elderly patients receiving chemotherapy is warranted. Female gender was also a risk for decreased muscle mass.…”

Section: Discussionmentioning

confidence: 99%

The impact of skeletal muscle mass on survival outcome in biliary tract cancer patients

et al. 2018

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Low skeletal muscle mass is frequently observed in cancer patients and is known to be a poor prognostic factor for survival outcomes. The purposes of our study were to determine the prevalence of sarcopenia and its relation to mortality in biliary tract cancer. Body composition measurements (skeletal muscle index, total fat mass, bone mineral content) were evaluated by using dual-energy x-ray absorptiometry in 75 biliary tract cancer patients before chemotherapy. Muscle strength was measured by handgrip strength and gait speed. Overall survival and its associated factors were determined. The mean appendicular muscle mass was 17.8±2.7 kg in men and 14.0±2.1 kg in women (p < 0.05). Sarcopenia was diagnosed in 46 patients (61.3%) and higher proportion of men was classified as sarcopenia than women (69.0% vs 35.3%, p < 0.05). Multivariable analysis adjusted for chemotherapy regimen and age revealed that high appendicular muscle mass independently predicted better survival outcomes (HR 0.40; 95% CI, 0.18 to 0.88; p = 0.023). Sarcopenia is common in biliary tract cancer patients and low appendicular muscle mass was associated with poor survival outcome.

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Section: Discussionmentioning

confidence: 99%

The impact of skeletal muscle mass on survival outcome in biliary tract cancer patients

et al. 2018

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“…e incidence of elderly cancer is also increasing since aging is one of the important risk factors for cancer. Between 1993 and 2012, the proportion of elderly cancer increased from 30 percent to 46 percent from the first to second decade [2].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Geriatric Syndromes in Elderly Cancer Patients Receiving Chemotherapy

Limpawattana

Phimson

Sookprasert

et al. 2020

Current Gerontology and Geriatrics Research

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The number of elderly patients with cancer is growing. Our study goals were to determine the prevalence of geriatric syndromes in elderly cancer patients receiving chemotherapy and its related factors using a basic geriatric screening tool. A cross-sectional study using the basic geriatric screening tool was conducted to survey geriatric problems in a population of elderly cancer patients receiving chemotherapy. There were 85 participants who were ≥60 years old. Descriptive statistics and regression analyses were used. The prevalence of having at least one geriatric syndrome was 58.8% (50 out of 85 cases). Depression was the most common component both in male and female patients. Age ≥65 years old was significantly associated with the geriatric syndrome (AOR 4.23, p=0.018), and a factor associated with depression was underweight (BMI<18.5 kg/m2) (AOR 13.2, p=0.003). In summary, geriatric syndromes are common in elderly cancer patients. Screening for geriatric syndrome adds substantial data on the assessment of elderly cancer patients, even those with a good performance status.

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“…In recent years, many countries are facing an aging society as the proportion of people aged over 65 years is growing tremendously 1. The number of elderly cancer patients has also been growing simultaneously 2…”

Section: Introductionmentioning

confidence: 99%

<p>Perioperative outcomes in elderly patients undergoing nephrectomy for renal cell carcinoma</p>

Sirithanaphol

Pachirat

Rompsaithong

et al. 2019

RRU

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Purpose To determine if age should be considered a relative contraindication to surgery for safety reasons. Methods Renal cell carcinoma (RCC) patients who underwent nephrectomy from January 2007 to December 2017 were analyzed retrospectively. Patients were grouped into age<65 and age≥65 years. The demographic data, surgical outcomes, complication, hospital stay, blood loss, and survival were compared between the two groups. Results A total of 101 patients were included; 74 in the younger group, and 27 in the older group. Compared to the young group, lower BMI, higher anemia, higher ASA grade, and comorbidities were frequent in the elderly. The operative time, blood loss, and renal function decline were comparable between two age groups. The complication rates in the older and younger group were 22% and 12%, respectively. The survival time was shorter in older patients compared to the younger ones; hazard ratio 2.25; 95%CI 1.08–4.69, p -value=0.031. Conclusion Nephrectomy in elderly patients is safe and feasible and preoperative assessment along with diligent postoperative care may further increase survival. Age alone cannot be regarded as a contraindication for nephrectomy in RCC.

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Hospital-based Population of Elderly Cancer Cases in Northeastern Thailand

Cited by 8 publications

References 9 publications

The impact of skeletal muscle mass on survival outcome in biliary tract cancer patients

The impact of skeletal muscle mass on survival outcome in biliary tract cancer patients

Prevalence of Geriatric Syndromes in Elderly Cancer Patients Receiving Chemotherapy

<p>Perioperative outcomes in elderly patients undergoing nephrectomy for renal cell carcinoma</p>

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