Hormonal changes around bovine luteolysis

Peterson, A. J.; Fairclough, R. J.; Payne, E.; Smith, J. F.

doi:10.1016/s0090-6980(75)80015-3

Cited by 88 publications

(41 citation statements)

References 17 publications

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“…During prepartal luteolysis, i.e. 36-48 h prior to birth, the increase in PGF 2a or of its major metabolite 15-keto-13,14-dihydro PGF 2a (PGFM) over basal levels is still minimal (Königsson et al 2001), and PGFM profiles in maternal peripheral blood are distinctly different from luteolysis in cyclic cows, where pronounced prostaglandin spikes of endometrial origin are observed preceding or concomitant with luteolysis (Peterson et al 1975, Kindahl et al 1976, Vighio & Liptrap 1986. Thus, the only clear role that can be attributed to the substantial increase in PGF 2a or PGFM during the immediate peripartal period , Edqvist et al 1978, Bosu et al 1984, Meyer et al 1989 seems to be related to myometrial activity.…”

Section: Introductionmentioning

confidence: 99%

Investigations into the mechanisms controlling parturition in cattle

Shenavai

Preissing²,

Hoffmann³

et al. 2012

Reproduction

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A pronounced increase in fetal cortisol concentrations stimulating an increase in estrogen production at the expense of progesterone precursors in the placenta, luteolysis, and progesterone withdrawal is considered as a key event during the complex signal cascade leading to the initiation of parturition in cattle. However, there are many questions concerning the exact functional and/or temporal relationships between these individual processes which finally result in the expulsion of the calf and the timely release of the placenta. Thus, parturition was induced in 270-day pregnant cows using the progesterone receptor blocker aglepristone (group AG, nZ3), the prostaglandin F 2a analog cloprostenol (group PG, nZ4), and the glucocorticoid dexamethasone (group GC, nZ4) to characterize the effect on maternal steroid and prostaglandin levels and to identify immediate subsequent changes in placental morphology and gene expression as compared with untreated controls sampled on day 272 (group D272, nZ3) and cows during normal parturition (group NT, nZ4). All calves of the treatment groups were born on days 271-272, whereas gestational length in NT cows was 280.5G1.3 days. However, none of the treatments significantly induced the prepartal remodeling of placentomes characterized by a decline in trophoblast giant cells and reduction of the caruncular epithelium. Data on placental CYP17 and COX2 expression confirm that these key enzymes are upregulated by GC, whereas placental aromatase expression was not affected by any treatment. Maternal progesterone and prostaglandin profiles suggest differential effects of the treatments on luteal function and placental or uterine prostaglandin production. The results provide new information on the initiation of parturition in cattle but raise many new questions.

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Section: Introductionmentioning

confidence: 99%

Investigations into the mechanisms controlling parturition in cattle

Shenavai

Preissing²,

Hoffmann³

et al. 2012

Reproduction

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“…From histological criteria it is thought that the number of non-atretic follicles > 5-0 mm in diameter is low (^3 per cow) due to a high incidence of atresia in follicles enlarging from 2 to 5 mm in diameter (Rajakoski, 1960;Scaramuzzi et al, 1980). Androstenedione, testosterone and oestradiol are major secretory products of bovine follicles and their concentrations in peripheral plasma fluctuate markedly, and often asynchronously, both within days and between each day of the oestrous cycle (Dobson & Dean, 1974; Lemon & Saumande, 1974;Peterson, Fairclough, Payne & Smith, 1975;Peterson, Fairclough & Smith, 1978; Wise, Caton, Thatcher, Lehrer & Fields, 1982). However, it has been difficult to extrapolate from hormone concentrations in peripheral plasma, the degree of follicular activity within the ovary.…”

Section: Introductionmentioning

confidence: 99%

Some aspects of thecal and granulosa cell function during follicular development in the bovine ovary

McNatty¹,

Heath²,

Henderson³

et al. 1984

Reproduction

180

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“…Endometrial PGE 2 and PGF 2α secretion in response to OT during the estrous cycle PGE2 concentration in the culture medium was higher than that of PGF2α from the early I (PGE2, 0.45 ± 0.04 µg/g tissue; PGF2α, 0.17 ± 0.02 µg/g tissue) to the late luteal stage (PGE2, 0.44 ± 0.03 µg/g tissue; PGF2α, 0.28 ± 00.2 µg/g tissue), and declined at the regressed stage (PGE2, 0.13 ± 0.01 µg/g tissue; Fig. 3).…”

Section: Time-and Dose-dependent Effects Of Ot On Pgf 2α Secretion Frmentioning

confidence: 99%

Secretion of Prostaglandins E<sub>2</sub> and F<sub>2α</sub> by the Bovine Endometrium in Response to Oxytocin during the Estrous Cycle

Miyamoto

Skarżyński

Uenoyama

et al. 1998

Journal of Reproduction and Development

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Hormonal changes around bovine luteolysis

Cited by 88 publications

References 17 publications

Investigations into the mechanisms controlling parturition in cattle

Investigations into the mechanisms controlling parturition in cattle

Some aspects of thecal and granulosa cell function during follicular development in the bovine ovary

Secretion of Prostaglandins E<sub>2</sub> and F<sub>2α</sub> by the Bovine Endometrium in Response to Oxytocin during the Estrous Cycle

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Hormonal changes around bovine luteolysis

Cited by 88 publications

References 17 publications

Investigations into the mechanisms controlling parturition in cattle

Investigations into the mechanisms controlling parturition in cattle

Some aspects of thecal and granulosa cell function during follicular development in the bovine ovary

Secretion of Prostaglandins E<sub>2</sub> and F<sub>2&alpha;</sub> by the Bovine Endometrium in Response to Oxytocin during the Estrous Cycle

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Secretion of Prostaglandins E<sub>2</sub> and F<sub>2α</sub> by the Bovine Endometrium in Response to Oxytocin during the Estrous Cycle