This is an overview on the medical problems, which might occur in the honeymoon period. The medical problems include several uncommon conditions .The most discussed ones in the medical literature are honeymoon cystitis and vaginismus .Future couples are also prone to skin diseases from overuse of cosmetics before wedding. A particular attention, in our paper, is given to the potential sexual injuries which may occur to the couples in this period together with a discussion on how to decrease their occurrence.