Homeopathic Remedies in COVID-19: Prognostic Factor Research

Manchanda, Raj K; Miglani, Anjali; Gupta, Meeta; Meena, Baljeet Singh; Chadha, Vishal; Joseph, Franco; Kalsi, Amrit; Konthembath, Pramod; Sharma, Kavita; Rama, Kamsali Nadigadda; Kaur, Prabhjeet; Kannoth, Jithesh Thavarayil; Nagrath, Cheshta; Jethani, Anju; Aniyeri, Shajimol Nellikka; Chawla, Anu; Ray, Malaya Kumar; Ghuliani, Manjula; Kudiyarasu, Ram Kumar; Naskar, Shruti; Bala, Sudha; Sharma, Brender

doi:10.1055/s-0041-1725989

Cited by 22 publications

(36 citation statements)

References 23 publications

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“…18 Cases with inadequate information, or in which a causal relationship between the medicine and the outcome could not be established, were therefore excluded from the analysis. A set of selection criteria based on the Modified Naranjo Criteria (MNC) 27 and our previous study on COVID cases 19 was adopted, wherein only four out of the 10 domains of MNC were considered. The criteria were:…”

Section: Methodsmentioning

confidence: 99%

Homeopathic Medicines in Second Wave of COVID-19: Prognostic Factor Research

et al. 2022

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Background/Objective The clinical profile and course of COVID-19 evolved perilously in a second wave, leading to the use of various treatment modalities that included homeopathy. This prognostic factor research (PFR) study aimed to identify clinically useful homeopathic medicines in this second wave. Methods This was a retrospective, multi-centred observational study performed from March 2021 to May 2021 on confirmed COVID-19 cases who were either in home isolation or at COVID Care Centres in Delhi, India. The data were collected from integrated COVID Care Centres where homeopathic medicines were prescribed along with conventional treatment. Only those cases that met a set of selection criteria were considered for analysis. The likelihood ratio (LR) was calculated for the frequently occurring symptoms of the prescribed medicines. An LR of 1.3 or greater was considered meaningful. Results Out of 769 confirmed COVID-19 cases reported, 514 cases were selected for analysis, including 467 in home isolation. The most common complaints were cough, fever, myalgia, sore throat, loss of taste and/or smell, and anxiety. Most cases improved and there was no adverse reaction. Certain new symptoms, e.g., headache, dryness of mouth and conjunctivitis, were also seen. Thirty-nine medicines were prescribed, the most frequent being Bryonia alba followed by Arsenicum album, Pulsatilla nigricans, Belladonna, Gelsemium sempervirens, Hepar sulphuris, Phosphorus, Rhus toxicodendron and Mercurius solubilis. By calculating LR, the prescribing indications of these nine medicines were ascertained. Conclusion Add-on use of homeopathic medicines has shown encouraging results in the second wave of COVID-19 in integrated care facilities. Further COVID-related research is required to be undertaken on the most commonly prescribed medicines.

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Section: Methodsmentioning

confidence: 99%

Homeopathic Medicines in Second Wave of COVID-19: Prognostic Factor Research

et al. 2022

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“…Similarly, in another report Bryonia alba Linn. and Arsenicum album have been shown to be frequently prescribed (25).…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics based homeopathic Remedy Profiling of COVID-19 Patients: A Retrospective Cohort Study

Aphale¹,

Sharma²,

Yeola³

et al. 2022

IJAM

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Objective: The objective of the study was to recognize core symptoms associated with COVID-19 positivity, its impact on mental health of patients and to identify indicated homeopathic remedies for COVID-19. Methods: In this pilot study, 25 confirmed COVID-19 patients admitted at Dedicated COVID Hospital (DCH) established under Dr. D Y Patil Vidyapeeth campus took part in survey questionnaire entitled as “Health impact survey for clinical features and patient profiles of COVID 19: Based on Homoeopathic perspective” observed by three independent observers. Based on the survey, specificity and sensitivity of symptoms was analyzed by three independent physicians to perform remedy analysis in order to identify indicated homeopathic medicines for COVID-19 in mild to moderate cases. Results: A total of 25 patients were included in study. Out of 25, 16 patients did not have any co-morbidity while 9 patients had diabetes, blood pressure or thyroid as one of the co-morbidities. The mean age of the patients was 39.4 years ± 12.6 where mean age of patients without co-morbidity was significantly lower than the patients with co-morbidities. The major symptoms were found to be fever (76%), cough (76%), shortness of breath (72%), sore throat (56%), fatigue (80%), loss of smell (40%) and Loss of taste(48%). Likelihood ratio of a positive test was found to be higher for Loss of smell, Loss of taste and Cough. Mixed and contrasting responses were reported by the study subjects on mental health impact. Majority of patients showed mild negative impact on mental health. In remedy analysis total 6 homeopathic medicines were observed with most commonly indicated being Carbo vegetabilis (70.66%), Antimonium tartaricum (10.66%), Arsenic album (9.33%) and Bryonia alba Linn. (4%) in 30C potency. Conclusion: The observation from current study demonstrate that fever, cough, shortness of breath, sore throat, fatigue, loss of smell and Loss of taste are most common symptoms associated with COVID-19 and Carbo vegetabilis, Antimonium tartaricum, Arsenic album and Bryonia alba Linn. are most frequently indicated homeopathic medicines for COVID-19.

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“…During the write-up of the current report, however, we noted commentary about Arsenicum album, suggesting some importance of this homeopathic medicine in prophylaxis and/or treatment, even in cases with co-morbidities. 30,31 To the best of our knowledge, several studies, including randomized controlled trials, are still under way 31though none of them seemingly in the occupational setting. Therefore, there are no effectiveness data available for the purposes of comparison.…”

Section: Discussionmentioning

confidence: 99%

Homeopathy for COVID-19 Prevention: Report of an Intervention at a Brazilian Service Sector Company

et al. 2021

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Background COVID-19 quickly became a serious public health problem worldwide, with serious economic and social repercussions. Homeopaths around the world have been studying to find a genus epidemicus (GE) medicine that might help in the prevention and treatment of this disease. Objective To compare the incidence of COVID-19 between employees who received or did not receive a homeopathic GE medicine for disease prevention. Methods Retrospective cohort analysis. The study population comprised all employees of a service sector company in São Paulo, Brazil, and followed up by the corporate Occupational Health department. Intervention consisted of administering Arsenicum album 30cH in a one-weekly dose. Primary outcome was incidence of COVID-19 during 3-months' follow-up (April to July, 2020). Results We analyzed 1,642 of 1,703 employees without previous diagnosis of COVID-19 at onset of the study period: 53.34% of employees were referred to telework at home and did not receive intervention (Group 1, G1); 24.66% remained working on-premises in the state of São Paulo and received the intervention (Group 2, G2); 21.98% remained working on company premises in other states and did not receive intervention (Group 3, G3). Incidence rate of COVID-19 was respectively 13.35%, 0.74%, and 67.87% (p < 0.001). The odds ratio of being infected in (1) G3 versus G1 was 13.70 (95% confidence interval [CI], 10.21 to 18.39), (2) G3 versus G2 was 283.02 (95% CI, 88.98 to 900.18), and (3) G1 versus G2 was 20.66 (95% CI, 6.53 to 65.39). Limitations The present is a retrospective analysis of a real-world experience. We could not ensure direct observed treatment, and neither could we control adherence to general prevention measures outside company premises. Conclusion The incidence of COVID-19 was significantly lower amongst on-premises employees who received the GE medication in comparison to workers who did not receive the intervention (those either at other company premises or teleworking at home).

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Homeopathic Remedies in COVID-19: Prognostic Factor Research

Cited by 22 publications

References 23 publications

Homeopathic Medicines in Second Wave of COVID-19: Prognostic Factor Research

Homeopathic Medicines in Second Wave of COVID-19: Prognostic Factor Research

Clinical characteristics based homeopathic Remedy Profiling of COVID-19 Patients: A Retrospective Cohort Study

Homeopathy for COVID-19 Prevention: Report of an Intervention at a Brazilian Service Sector Company

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