Hollow-fibre liquid-phase microextraction and gas chromatography-mass spectrometric determination of amphetamines in whole blood

Bombana, Henrique Silva; Santos, Marcelo Filonzi dos; Muñoz, Daniel Romero; Leyton, Vilma

doi:10.1016/j.jchromb.2020.121973

Cited by 21 publications

(13 citation statements)

References 31 publications

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“…Bombana et al. [ 53 ] determined amphetamine, methamphetamine, fenproporex, 3,4-methylenedioxymethamphetamine, 3,4-methylene-dioxyamphetamine, and 3,4-methylene-dioxy-ethylamphetamine in whole blood samples. Ask et al.…”

Section: Sample Preparation Techniques In Bioanalyticsmentioning

confidence: 99%

“…Table 1 [ 7 , 31 , [34] , [35] , [36] , [41] , [42] , [43] , [44] , [48] , [49] , [50] , 53 , 54 , 59 , 61 , 65 , 66 , 78 , 79 , 82 , 86 , 89 , 90 , 100 , 105 , 113 , 114 , 117 , 124 , 126 , [128] , [129] , [130] , [132] , [133] , [134] , [135] , [136] , 141 , 142 , 145 , 146 , 148 , [152] , [153] , [154] , [155] , 160 , 163 , 164 , 195 , 196 ] summarizes the sample preparation techniques and analytes extracted from biological matrices using sophisticated analytical techniques.…”

Section: Sample Preparation Techniques In Bioanalyticsmentioning

confidence: 99%

See 1 more Smart Citation

Current developments of bioanalytical sample preparation techniques in pharmaceuticals

Ingle

Zeng

Jiang

et al. 2022

Journal of Pharmaceutical Analysis

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Section: Sample Preparation Techniques In Bioanalyticsmentioning

confidence: 99%

Section: Sample Preparation Techniques In Bioanalyticsmentioning

confidence: 99%

Current developments of bioanalytical sample preparation techniques in pharmaceuticals

Ingle

Zeng

Jiang

et al. 2022

Journal of Pharmaceutical Analysis

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“…Despite the prohibition, these drugs are sold illegally and are being consumed by people. According to the United Nations Office on Drugs and Crime (UNODC) reports, about 5.5% of the world's population (271 million people) between ages of 15 and 64 years have consumed some type of drug at least once in 2017 [3]. Due to health and legal entails of their abuse, the growing popularity, increased production, and commercialization of stimulant substances, these materials cause significant social and public security problems [4].…”

Section: Introductionmentioning

confidence: 99%

Application of HKUST‐1 metal‐organic framework as coating for headspace solid‐phase microextraction of some addictive drugs

Baheri

Yamini

Shamsayei

et al. 2021

J of Separation Science

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In the present study, a copper-based metal-organic framework (HKUST-1) was used first time for preconcentration trace amounts of addictive drugs in biological samples. HKUST-1 was synthesized and coated onto the surface of stainless steel wire. The prepared coating was used in headspace solid-phase microextraction method coupled with gas chromatography-mass spectrometry for preconcentration and determination of some addictive drugs in biological fluids. Prepared coating shows good extraction efficiency due to large surface area, and π-π stacking interaction with selected analytes. Under optimum conditions, the method was validated with a reasonable determination coefficient (R 2 > 0.9961) and suitable linear dynamic range (0.5-1000 μg L −1 ). Also, the limits of detections were obtained in the range of 0.1-0.4, 0.2-0.6, and 0.4-0.7 μg L −1 for water, urine, and plasma samples, respectively. The limits of quantification of present method were obtained in the range 0.5-1.3, 0.7-1.5, and 1.0-1.9 μg L −1 in water, urine, and plasma samples, respectively. The intra-day and inter-dye single fiber and fiber to fiber relative standard deviations were observed in the range 3.0-13.9% and 3.5-12.3%, respectively. Finally, the present method was applied for the determination of the drugs in biological samples.

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“…Improvement of FAB Biocompatibility by Purification Capability of LPME. It is well known that LPME possessed excellent purification capacity toward complex samples, 24,25 which was especially important for the LPME-FAB system since traditional FABs cannot be directly applied for biological samples. The schematic demonstration of the purification capability of the LPME-FAB system is presented in Figure 5A.…”

mentioning

confidence: 99%

“…Membrane-based liquid-phase microextraction (LPME) could provide sufficient sample cleanup and preconcentration capacities for the targets in biological samples. , In a typical LPME process, the analyte is first extracted from a sample into a supported liquid membrane (SLM) and further into an acceptor solution . In this process, the low-level target in biological samples can be preconcentrated in the simple acceptor solution, making it a promising technique for future integration with FABs.…”

mentioning

confidence: 99%

Versatile Integration of Liquid-Phase Microextraction and Fluorescent Aptamer Beacons: A Synergistic Effect for Bioanalysis

et al. 2021

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Fluorescent aptamer beacons (FABs) are a major category of biosensors widely used in environmental analysis. However, due to their low compatibility, it is difficult to use the common FABs for biological samples. To overcome this challenge, construction of FABs with complex structures to adapt the nature of biological samples is currently in progress in this field. Unlike previous works, we moved our range of vision from the FAB itself to the biological sample. Inspired by this idea, in this work, flat membrane-based liquid-phase microextraction (FM-LPME) with sufficient sample cleanup and preconcentration capacities was integrated with FABs. With the merits of both FM-LPME and FABs, the integrated LPME-FAB system displayed a clear synergistic enhancement for target analysis. Specifically, LPME in the LPME-FAB system provided purified and enriched Hg 2+ for the FAB recognition, while the FAB recognition event promoted the extraction efficiency of LPME. Due to superior performances, the LPME-FAB system achieved highly sensitive analysis of Hg 2+ in urine samples with a detection limit of 27 nM and accuracies in the range of 98−113%. To the best of our knowledge, this is the first time that an integrated LPME-FAB system was constructed for target analysis in biological samples. We believe that this study will provide a new insight into the next generation of biosensors, where the integration of sample preparation with detection probes is as important as the design of complex probes in the field of bioanalysis.

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Hollow-fibre liquid-phase microextraction and gas chromatography-mass spectrometric determination of amphetamines in whole blood

Cited by 21 publications

References 31 publications

Current developments of bioanalytical sample preparation techniques in pharmaceuticals

Current developments of bioanalytical sample preparation techniques in pharmaceuticals

Application of HKUST‐1 metal‐organic framework as coating for headspace solid‐phase microextraction of some addictive drugs

Versatile Integration of Liquid-Phase Microextraction and Fluorescent Aptamer Beacons: A Synergistic Effect for Bioanalysis

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