1999
DOI: 10.1016/s0198-8859(99)00112-3
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HLA-DRB1∗ and allergy to Parietaria: linkage and association analyses

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Cited by 11 publications
(9 citation statements)
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“…DQB1*0202 has been related to nasal polyposis, 33 DRB1*0301 to poor response to grass pollen specific immunotherapy, 34 and DRB1*1101 to mitesensitive bronchial asthma, 35 as well as to high levels of specific IgE against Parietaria major allergen Par o 1. 36 More interestingly, the high frequency of DRB1*0701 (DR7) phenotype among patients with spina bifida with latex or hevein responsiveness, 16 together with the protective effect that-according to our results-DRB1*0701 seems to exert against latex-fruit allergy, could further explain the lower prevalence of latex-fruit allergy in patients with latex allergy and spina bifida compared with patients without spina bifida.…”
Section: Discussionsupporting
confidence: 52%
“…DQB1*0202 has been related to nasal polyposis, 33 DRB1*0301 to poor response to grass pollen specific immunotherapy, 34 and DRB1*1101 to mitesensitive bronchial asthma, 35 as well as to high levels of specific IgE against Parietaria major allergen Par o 1. 36 More interestingly, the high frequency of DRB1*0701 (DR7) phenotype among patients with spina bifida with latex or hevein responsiveness, 16 together with the protective effect that-according to our results-DRB1*0701 seems to exert against latex-fruit allergy, could further explain the lower prevalence of latex-fruit allergy in patients with latex allergy and spina bifida compared with patients without spina bifida.…”
Section: Discussionsupporting
confidence: 52%
“…In low IgE responder patients (low total IgE and/or monosensitized), the allergic sensitization depends more closely on HLA‐DR or DQ molecules than in patients with high total IgE or polysensitized . In another study, the Parietaria IgE antibody response was associated with DRB1*1104 in patients with low total IgE and with DRB1*1101 in patients with high total IgE . Genetic restrictions of Ole e1 are associated with total serum IgE levels .…”
Section: Mono‐ and Polysensitization Against Allergensmentioning
confidence: 92%
“…In low‐IgE responder patients (low total IgE or monosensitized) the allergic sensitization depends more closely on HLA‐DR or DQ molecules than in patients with high total IgE or polysensitized (32, 33). In another study, the Parietaria IgE antibody response was associated with DRB1*1104 in patients with low total IgE and with DRB1*1101 in patients with high total IgE (34). HLA‐DR4 is a protective class II antigen against sensitivity to Ole e 1, the major antigen of olive pollen, and HLA‐DQ2 is a risk factor for it (35).…”
Section: Mono and Polysensitization Against Allergensmentioning
confidence: 98%