HLA-A, -B, -Cw and -DRB1 allele frequencies in an Ami population from Taiwan

High-resolution human leukocyte antigen (HLA) haplotypes and linkage disequilibrium of HLA-B and -C and HLA-DRB1 and -DQB1 alleles in a Taiwanese population

“…We have also revealed the presence of B*1518 in the donors in the Taiwanese marrow donor registry [21] and its cord blood units [4]. The average frequency of B*1518 in the Taiwanese population was relatively low (0.9% approximately) [19,20], which explains why it was not detected in the API ethnic group in the United States [3]. It is noteworthy that both B*1518 donors in this study carried Cw*0704.…”

“…Interestingly, haplotype A*1101-B*1518-Cw*0704, observed in the Taiwanese cohort, was not reported in the API group but was in the European, AA, and HIS ethnic groups of NMDP donors [3]. B*1518 was observed in the Taiwanese Hakka and Minna ethnicities but not in the Taiwanese indigenous population [19,20]. We have also revealed the presence of B*1518 in the donors in the Taiwanese marrow donor registry [21] and its cord blood units [4].…”

Y chromosome review of the Atayal and Truku Tribes of Taiwan and their relationship with other groups of East and Island Southeast Asia

“…Finally, more support to the pattern of distribution just described by Y and mitochondrial DNA analysis, is brought by the HLA gene system (Supplementary Text 1) which allowed differentiating non-AN_Tw from Minnan, Hakka and Pingpu groups, and suggested the occurrence of recent gene flow between these groups [4,14,18].…”

“…Y-STRs only data for Atayal and Truku are available throught Wu et al 2013 [11]. The corresponding HLA and mtDNA data to support our results were combined with data from multiple studies [2,5,12,14,15,[17][18][19]. The Atayal and Truku partial and complete mtDNA genomes are shown in Supplementary Table S2.…”