Abstract:HL-A typing was performed in 22 potential kidney recipients, 35 parents and 87 siblings.
Homozygosity for one or two HL-A antigens was present in about half of the patients with a phenotypic incomplete HL-A pattern. In 12 patients 23 HL-A identical siblings were found.
In one patient recombination of the paternal first and second locus of the HL-A system was observed. Mixed lymphocyte reactions (MLR) were carried out with 3 sibs and an unrelated donor. A difference at the first HL-A locus was accompanied by a … Show more
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