HIV-associated extrapulmonary tuberculosis in Thailand: epidemiology and risk factors for death

Kingkaew, Nara; Sangtong, Burachat; Amnuaiphon, Waraya; Jongpaibulpatana, Jessada; Mankatittham, Wiroj; Akksilp, Somsak; Sirinak, Chawin; Nateniyom, Sriprapa; Burapat, Channawong; Kittikraisak, Wanitchaya; Monkongdee, Patama; Varma, Jay K.

doi:10.1016/j.ijid.2008.11.013

Cited by 78 publications

(69 citation statements)

References 21 publications

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“…There was 1 (2%) mortality noted in our series and that too after the patient was discharged from hospital as compared to 59 (19%) in Nara Kingkaew, et al 34 case series.…”

Section: Observation and Resultscontrasting

confidence: 46%

Evaluation of pattern and treatment of osteoarticular tuberculosis in central India

Naik¹,

Dulani²,

Khan³

et al. 2020

IJOS

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Introduction: Tuberculosis the global epidemic continues to be a major health problem despite availability of effective chemotherapy. The main aim of the study was to analyse the pattern, clinical findings, diagnosis, and treatment options for osteoarticular tuberculosis at Tertiary care hospital so that proper treatment guidelines can be formulated for the patient. Materials and Methods: A prospective study was performed in the tertiary care. Patients clinically diagnosed as osteoarticular tuberculosis, all the patients who were regular on anti-tubercular treatment and follow-up and all the patients with radiological evidence matching with clinical profile were included in the study. All the patients who showed histopathological evidence in favor of osteoarticular tuberculosis were also included. The patients with only pulmonary tuberculosis, with extra pulmonary involvement, with no osteoarticular involvement were excluded from the study. Observation and Results: The age group of patient ranged from 1-80 years, mean age was 38.11 in males and 34.5 years in females with a total mean age of 36.96 years. Sex predominance was seen in males with 68%. The distribution of the patient according to occupation farmer category showed a maximum of 56%. Socio-economic class distribution according to modified kuppuswamy classification showed most patient belonged to Upper-Lower (IV) 82% and 18% belonged to lower-middle (III) category. Conclusion: Tuberculosis of the spine is still the most preferred site of osteoarticular tuberculosis. Spine patient usually require early surgical intervention especially those with neurological deficits. Outcomes may be maximized through early detection and treatment, although adequate results can still be achieved with salvage procedures in patients presenting with late stages of disease.

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“…There was 1 (2%) mortality noted in our series and that too after the patient was discharged from hospital as compared to 59 (19%) in Nara Kingkaew, et al 34 case series.…”

Section: Observation and Resultscontrasting

confidence: 46%

Evaluation of pattern and treatment of osteoarticular tuberculosis in central India

Naik¹,

Dulani²,

Khan³

et al. 2020

IJOS

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“…Although pulmonary tuberculosis is the predominant form of infection, extrapulmonary tuberculosis constitutes up to 20% of reported cases, approximately 1 to 5% of which are attributed to tuberculosis of the central nervous system (CNS-TB) (2). CNS-TB occurs primarily in childhood but significantly increases in adults under conditions of immune suppression, which are associated with considerable morbidity and mortality (3,4). Pathogenesis of CNS-TB is initiated as a secondary infection during hematogenous dissemination of pulmonary infection to the brain parenchyma (5).…”

mentioning

confidence: 99%

Neurons Are Host Cells for Mycobacterium tuberculosis

et al. 2014

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“…Consequently, HIV status should be defined if TBM is recognized [9]. Furthermore, sever immunosuppression, increases the odds of having TBM [36,37]. Leeds and al were reported that HIV infected patients with extrapulmonary TB and CD4 less than 100 were more likely to have TBM [4].…”

Section: Issn: 2373-8995mentioning

confidence: 99%

Tuberculous Meningitis in Patients Living with HIV

ELFane¹

2017

J Neurol Neurosurg

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Background: Tuberculosis Meningitis (TBM) is a devastating manifestation of tuberculosis (TB) caused by the hematogenous spread of Mycobacterium tuberculosis. TBM is particularly severe in HIV infected patients. In Morocco, TB and HIV are the main public health problems; the rate of TBM has not been well defined. The objective of this study was to describe the presentation and outcome of TBM during HIV infection in our department.

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HIV-associated extrapulmonary tuberculosis in Thailand: epidemiology and risk factors for death

Cited by 78 publications

References 21 publications

Evaluation of pattern and treatment of osteoarticular tuberculosis in central India

Evaluation of pattern and treatment of osteoarticular tuberculosis in central India

Neurons Are Host Cells for Mycobacterium tuberculosis

Tuberculous Meningitis in Patients Living with HIV

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