History of glucose monitoring: past, present, future

Klimek, Monika; Knap, Joanna; Reda, Mateusz; Masternak, Marta

doi:10.5281/zenodo.3397600

Cited by 2 publications

(2 citation statements)

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Section: Introductionmentioning

confidence: 99%

“…Frequent glucose monitoring is recommended for patients treated with insulinall patients with type 1 diabetes mellitus (T1D) and some patients with type 2 diabetes mellitus (T2D)so they can adjust insulin dose, depending on factors such as diet and exercise [10]. For many years, patients had to use test strips and finger-stick blood samples to monitor glucose levels [10]. However, this method has barriers that can be reduced with continuous glucose monitoring (CGM) and intermittently scanned continuous glucose monitoring (isCGM), particularly benefiting patients unable or unwilling to self-monitor blood glucose (SMBG) due to pain or discomfort [11].…”

Section: Introductionmentioning

confidence: 99%

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Adherence to glucose monitoring with intermittently scanned continuous glucose monitoring in patients with type 1 diabetes

et al. 2022

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Purpose This study aims to predict the Intermittently scanned continuous glucose monitoring (isCGM) adherence behavior of patients with Type 1 Diabetes. Methods Patients with Type 1 Diabetes mellitus using FreeStyle Libre™ System (FL), a isCGM device, that attended the “Insulin Infusion Pump clinic” at Centro Hospitalar de São João were enrolled and evaluated for sociodemographic and clinical characterization, beliefs and concerns about Diabetes Mellitus, as well as isCGM’s perceptions. Intermittently scanned continuous glucose monitoring data were collected to characterize monitoring patterns and to measure isCGM’s adherence—FL average of scans/day. Results Seventy-two patients with a mean of 30.36 years (sd=11.35) participate in this study. A median of 7 scans/day was performed. The adherence predictors found was Age (β = 0.191, p = 0.006), Time in target (β = 0.530, p = 0.002), isCGM Necessity (β = 2.631, p = 0.048), Body Mass Index (β = −0.549, p = 0.017) and Sex (β = −3.996; p = 0.011). Conclusions This study emphasizes the relevance of glucose monitoring adherence in disease control and shows that males of younger ages, presenting with higher body mass index levels, lower time in target, and reporting lower isCGM necessity are less adherent to isCGM. Therefore, these patients should be closely followed and object of personalized strategies to promote treatment adherence.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Adherence to glucose monitoring with intermittently scanned continuous glucose monitoring in patients with type 1 diabetes

et al. 2022

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Cucurbit[n]uril-Immobilized Sensor Arrays for Indicator-Displacement Assays of Small Bioactive Metabolites

Zhong

Kumar

et al. 2021

ACS Appl. Nano Mater.

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The patterned immobilization of chemosensors into nano/microarrays has often boosted utilization in diagnostics and environmental sensing applications. While this is a standard approach for biosensors, e.g., with antibodies, other proteins, and DNA, arraying is not yet adopted widely for supramolecular chemosensors which are still predominantly used in solution systems. Here we introduce the patterned immobilization of cucurbit[n]urils (CBn) into multiplexed microarrays and elucidate their prospects for the advancement of surface-bound indicator-displacement assays to detect small molecule analytes. The microarrays were generated by microchannel cantilever spotting of functionalized CBn and subsequent self-assembly of the corresponding indicator dyes from solution. Enhanced sensitivity of surface-bound microarrays was established in demonstrations with small bioactive metabolites (spermine, amantadine, and cadaverine) compared to bulk assays. Furthermore, the integration of the CBn/indicator microarrays into microfluidic channels provides an efficient route for real-time monitoring of the sensing process, allows easier handling, and reduces need for analyte volume. The concept was further extended to differential sensing of analytes on diplex or multiplex CBn/indicator microarrays, opening up a route for multicomponent sensing of small molecule analytes in complex liquids.

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History of glucose monitoring: past, present, future

Cited by 2 publications

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Adherence to glucose monitoring with intermittently scanned continuous glucose monitoring in patients with type 1 diabetes

Adherence to glucose monitoring with intermittently scanned continuous glucose monitoring in patients with type 1 diabetes

Cucurbit[n]uril-Immobilized Sensor Arrays for Indicator-Displacement Assays of Small Bioactive Metabolites

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