I am deeply grateful to my advisor, Prof. Marcio Sampaio, for his continuous support, guidance, and unwavering commitment to my academic and professional development. His expertise, invaluable insights, and willingness to share his knowledge have significantly influenced the outcome of this research. I would like to extend my sincere thanks to the Energy Production Innovation Center (EPIC), FAPESP and Equinor for their generous financial support throughout the course of this research. Their investment in this project has enabled me to pursue in-depth investigations and achieve meaningful results. I am grateful to the UNISIM group for providing the simulation models that were crucial for conducting this study. Their contribution has greatly enhanced the accuracy and reliability of the research outcomes. Additionally, I would like to acknowledge the Computer Modelling Group (CMG) for providing the essential licenses of the reservoir flow simulator. Lastly, I want to express my gratitude to the Polytechnic School of the University of São Paulo (USP) and the Laboratory of Petroleum Reservoir Simulation and Management (LASG) for providing the necessary infrastructure and resources that facilitated the progress of this research. Their commitment to academic excellence and dedication to fostering a conducive research environment have been invaluable. "Explore the world. Nearly everything is really interesting if you go into it deeply enough."