Historical Perspectives: Forty Years of Mechanical Ventilation ...Then and Now...

Philip, Alistair G. S.

doi:10.1542/neo.4-12-e335

Cited by 8 publications

(3 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Mechanical ventilation of the preterm newborn with respiratory insufficiency or respiratory failure has become one of the mainstays of neonatal care since Drs. Delivoria-Papadopoulos and Swyer described the use of endotracheal tubes to provide positive pressure ventilation to neonates in 1963 [1]. While potentially life-saving, prolonged invasive mechanical ventilation is associated with substantial healthcare cost and a variety of pulmonary and extrapulmonary complications including air leak syndromes, traumatic injury to the large airways, retinopathy of prematurity, and bronchopulmonary dysplasia [2,3].…”

Section: Introductionmentioning

confidence: 99%

Tidal volume transmission during non-synchronized nasal intermittent positive pressure ventilation via RAM® cannula

Matlock

Bai

Weisner³

et al. 2019

J Perinatol

View full text Add to dashboard Cite

Background Nasal intermittent positive pressure ventilation (NIPPV) is a widely used mode of support in neonates, during which ventilator inflations may or may not coincide with spontaneous breathing. Objective We tested the hypothesis that inflations delivered with NIPPV via RAM ® cannula and not accompanied by patient effort produce minimal tidal volume as measured by respiratory inductance plethysmography. Design/Methods Fourteen subjects were monitored while receiving NIPPV. We compared tidal volumes during ventilatorsupported breaths, unsupported breaths, and ventilator inflations not accompanied by patient effort (defined using electrical activity of the diaphragm). Results Mean tidal volumes in arbitrary units were 0.30 ± 0.22 in NIPPV inflations associated with patient effort and 0.27 ± 0.15 in spontaneous breaths without ventilator assistance (p = 0.82). Tidal volumes during ventilator-only inflations were 0.06 ± 0.04 (p < 0.005 vs. both ventilator-assisted and unassisted efforts). Conclusions NIPPV via RAM cannula produces minimal, clinically insignificant tidal volumes during non-spontaneous inflations.

show abstract

Section: Introductionmentioning

confidence: 99%

Tidal volume transmission during non-synchronized nasal intermittent positive pressure ventilation via RAM® cannula

Matlock

Bai

Weisner³

et al. 2019

J Perinatol

View full text Add to dashboard Cite

show abstract

“…A young doctor working at the Hospital for Sick Children in Toronto, Canada, Dr. Maria Delivoria-Papadopoulos , who, along with Paul Swyer, was the first to introduce assisted ventilation in neonates successfully, was also called. However, due to various reasons in that time era, it was not possible to get involved in the infant's care [2,3].…”

Section: Effect Of Imv On Neonatal Survivalmentioning

confidence: 99%

The Intertemporal Role of Respiratory Support in Improving Neonatal Outcomes: A Narrative Review

et al. 2021

View full text Add to dashboard Cite

Defining improvements in healthcare can be challenging due to the need to assess multiple outcomes and measures. In neonates, although progress in respiratory support has been a key factor in improving survival, the same degree of improvement has not been documented in certain outcomes, such as bronchopulmonary dysplasia. By exploring the evolution of neonatal respiratory care over the last 60 years, this review highlights not only the scientific advances that occurred with the application of invasive mechanical ventilation but also the weakness of the existing knowledge. The contributing role of non-invasive ventilation and less-invasive surfactant administration methods as well as of certain pharmacological therapies is also discussed. Moreover, we analyze the cost–benefit of neonatal care-respiratory support and present future challenges and perspectives.

show abstract

“…(17) Establishing criteria for earlier respiratory support soon produced improvements in ventilation. There, she revealed the extended experience she had acquired in Greece in treating the respiratory failure of the poliomyelitis-affected children.…”

Section: Foreign Medical Graduatesmentioning

confidence: 99%

Historical Perspectives

Toubas¹

2011

NeoReviews

View full text Add to dashboard Cite

Twenty vibrant years, starting in 1960, marked the beginning of modern neonatology, and during those years, the participation of women in medical science increased amid a flurry of national and international social and historical events. The availability of grants allowed the exploration of the newborn infant's biology. Young women pediatricians and scientists studied brain development, and newborn intensive care started to proliferate. The virtues of early feeding were recognized. Infections were actively prevented and treated. Assisted ventilation provided life support to infants whose lungs could not remain inflated due to surface tension deficiency. Noninvasive measurement of PaO 2 signaled a kinder approach to oxygenation monitoring and newborn care. Advances were made in the understanding of jaundice and the prevention of kernicterus. Sudden infant death syndrome came under question, leading to studies on the control of respiration. Many of these outstanding women were rewarded, but leadership academic positions frequently remained out of the reach of other deserving women. By the beginning of 1980, the number of women in neonatal-perinatal medicine began to climb exponentially.

show abstract

Historical Perspectives: Forty Years of Mechanical Ventilation ...Then and Now...

Cited by 8 publications

References 18 publications

Tidal volume transmission during non-synchronized nasal intermittent positive pressure ventilation via RAM® cannula

Tidal volume transmission during non-synchronized nasal intermittent positive pressure ventilation via RAM® cannula

The Intertemporal Role of Respiratory Support in Improving Neonatal Outcomes: A Narrative Review

Historical Perspectives

Contact Info

Product

Resources

About