2014
DOI: 10.25100/cm.v45i4.1656
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Histoplasmosis laríngea: reporte del primer caso en Colombia

Abstract: Laryngeal histoplasmosis is a fungal infection that is frequent in Colombia. Laryngeal histoplasmosis usually occurs in immunocompromised patients through the dissemination of the fungus from the lungs to other organs. Histoplasmosis isolated laryngeal (primary) is rare. If a patient presents with a history of immunosuppression by renal transplant, primary laryngeal histoplasmosis with supraglottic granulomatous inflammation that was treated with amphotericin B and Itraconazole, with complete resolution of lar… Show more

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Cited by 15 publications
(7 citation statements)
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“…Presence of oral ulcers is also a clinical clue towards diagnosis. We also found some rare organs involved like pericardium and vocal cords, which have been reported previously but are considered rare …”
Section: Discussionsupporting
confidence: 80%
“…Presence of oral ulcers is also a clinical clue towards diagnosis. We also found some rare organs involved like pericardium and vocal cords, which have been reported previously but are considered rare …”
Section: Discussionsupporting
confidence: 80%
“…Disseminated forms are rare, occurring mainly in children less than 2 years, elderly and immunocompromised individuals. In healthy children, this condition is usually self-limiting, rarely requiring treatment but immunocompromised children, as the present case, are prone to develop more severe disease [8]. Histoplasma capsulatum infection involving the pharynx and larynx is a rare manifestation and is usually associated with mucocutaneous form of chronic disseminated spread.…”
Section: Discussionmentioning
confidence: 71%
“…Diagnosis of laryngeal histoplasmosis is rarely based on clinical examination and a set of differential diagnosis needs to be considered like amyloidosis, tuberculosis, lymphoma, syphilis, and sarcoidosis [2,8]. Definitive diagnosis is based on histopathological examination of sputum, BAL, smears from ulcers in oral cavity, urine, bone marrow biopsies or oral/laryngeal masses with hematoxylin and eosin (H&E), periodic acid Schiff, and Gomori's methenamine-silver nitrate stain, which can be confirmed by the growth of the fungi on Sabouraudchloramphenicol medium at 27°C for 10-14 days [1].…”
Section: Discussionmentioning
confidence: 99%
“…The vascular ectasia in this patient had extended from the proximal of esophagus to the larynx with the finding of upper airway obstruction, which could be caused by infections, structural anomalies such as laryngomalacia, congenital vocal cord paralysis, subglottic stenosis, hemangioma, or cystic hygroma. 11,12 There have been four adult cases of vascular ectasia in esophagus reported in the literature. The case presented here is the first pediatric case of vascular ectasia accompanied with submicroscopic chromosomal anomalies.…”
Section: Discussionmentioning
confidence: 99%