Histoplasmomas encefálicos múltiplos: estudo autópsico de um caso

Abstract

Report of the case of a 28-years-old black woman who developed changes in behavior followed by neurological alterations. The CT scans of the brain revealed multiple calcified granulomas. The patient died and the autopsy showed granulomatous lesions with central caseation in the brain. Microscopical examination disclosed numerous Histoplasma capsulatum. This is the first case of histoplasmoma of the brain described in Brazil.

Histoplasmosis in Rio Grande do Sul, Brazil: a 21-year experience

“…Before 1980 only three small surveys of histoplasmin skin test were performed 6,10,11 and four cases of histoplasmosis were reported 1,5 or quoted 2 in natives of the State of Rio Grande do Sul. However, since 1981 thirty nine cases of the mycosis have been published 3,[7][8][9]12,14,16,[18][19][20][21][22][23][24] . In addition, in 1996 a histoplasmin skin test survey revealed 89 per cent of reactors amongst young men aged between 17 to 19 years of age, living in the Jacuí River valley 26 .…”