Histoplasma capsulatum in peripheral blood smear

Singh, Nilanchali; Nagendra, Sanjai

doi:10.1136/bcr.05.2009.1877

Cited by 3 publications

(2 citation statements)

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“…Within the major deformation zone, the outside half of the round corner die ECAP process moves more swiftly than the inner half. The corner gap caused by the hardening exponent was decreased by the strain rate sensitivity [50]. The relative effects of strain hardening exponent and strain-rate sensitivity had a considerable impact on the deformation inhomogeneity [51].…”

Section: Discussionmentioning

confidence: 96%

Impact design of die parameters on Severe plastic deformation during Equal channel angular pressing: An overview

Singh,

Agrawal,

Verma

et al. 2023

E3S Web Conf.

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Equal channel angular pressing causes less uniform deformation than simple shear, even though its not as obvious as with other metal forming procedures. Investigation is done into how internal and external factors affect the deformity inhomogeneity through Equal .channel angular pressing. Finite element analysis of plastic deformity are integrated with die corner angle and the strain harden ability of metallic workpiece. The material characteristics are significantly influenced by the type of plastic shear deformation that occurs through Equal channel angular pressing and this is primarily impacted by the die geometry, the properties of the material and the process factors. Segmenting the workpiece into a front transient zone, end transient zone, outer less sheared zone and the remaining shear deforming zone allowed researchers to examine the uneven strain distribution throughout the workpiece. The deformed geometry for the non-hardening and it was assumed that rate-insensitive materials would be largely homogeneous. In materials that are strain-rate sensitive, gaps between the upper and lower channels developed, whereas strain-hardening materials experienced the corner gap. The strain hardening and implications of strain-rate sensitivity exponent had a considerable impact on the deformation inhomogeneity. Metals having an ultrafine grain microstructure can be created by severe plastic deformation. The FE models were used to affect the process and they all took as inputs the material properties, load variation, Different velocity and boundary conditioned. For the purpose of evaluating the impact of the channel angle on the AA5083 sample, The FE analysis produced the value of strain distribution. When the channel angle was 1200, there was less strain overall, but there was also less concentrated stress in the channel corner area.

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Section: Discussionmentioning

confidence: 96%

Impact design of die parameters on Severe plastic deformation during Equal channel angular pressing: An overview

Singh,

Agrawal,

Verma

et al. 2023

E3S Web Conf.

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“…This finding is usually related to severe cases. Round-form organisms of 3-4 µm, with basophilic cytoplasm and a false impression of a peripheral capsule, are depicted inside the leukocytes 21 - 23…”

Section: Discussionmentioning

confidence: 99%

Co-infection of disseminated histoplasmosis and tuberculosis in an AIDS patient

Tomazini¹,

Bandeira²,

Aragão³

et al. 2013

ACR

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Histoplasmosis is a fungal disease caused by the dimorphic fungus Histoplasma capsulatum , recognized as an AIDS-defining illness since the Center for Disease Control’s revision criteria in 1985. This infection is reported to be present in 5-20% of AIDS patients, and in 95% of the cases it is manifested in its disseminated form. Serum antibodies and/or antigen research can make diagnosis, but the demonstration of the agent by culture or histopathological examination remains the gold standard methods. Co-infections in patients with AIDS are well known; however, reports on disseminated tuberculosis and histoplasmosis are scarce. The authors report the case of a female patient who presented a short-course history of weight loss, fever, and mild respiratory symptoms, with hepatosplenomegaly and lymphadenopathy. Laboratory workup called attention to anemia, altered liver, canalicular enzymes, liver function tests, high titer of lactate dehydrogenase (LDH), and pulmonary nodules on thoracic computed tomography. Incidental finding of yeast forms within the leukocytes during a routine blood cell count highlighted the diagnosis of histoplasmosis. The patient started receiving amphotericin B but succumbed soon after. The authors emphasize the possibility of this co-infection, the diagnosis of severe infection through the finding of yeast forms within peripheral leukocytes, and for the high titer of LDH in aiding the differential diagnosis.

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