Histopathology Of Experimental Photocoagulation in the Dog Eye*

Okun, Edward; Collins, Eleanor M.

doi:10.1016/0002-9394(62)93989-2

Cited by 28 publications

(4 citation statements)

References 16 publications

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“…5, 6). Terminal swellings on either side of interrupted axons in areas of intense photocoagulation have been previously reported (Okun and Collins, 1962;Marshall and Mellerio, 1967), but it was not appreciated until recently that such swellings arise through the interruption of the bidirectional flow of axoplasmic constituents along the axon. In an autoradiographic study of both laser and ischaemic lesions in pig retina it has been demonstrated that the swelling of damaged axons occurs as a passive response to the damming of axonal flow (McLeod et al, 1977).…”

Section: Secondary Responses To Laser Irradiationmentioning

confidence: 99%

A comparative histopathological study of argon and krypton laser irradiations of the human retina.

Marshall¹,

Bird²

1979

British Journal of Ophthalmology

180

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SUMMARY A series of comparative exposures to both argon and krypton lasers have been made at 3 locations in a human retina-the fovea, the macula, and intraretinal vessels. In the fovea argon irradiations resulted in damage to both the inner and outer retinal layers as a result of absorption within the pigment epithelium and the macular pigment, while krypton exposures damaged the outer retina and the choroid. In the macula both systems resulted in damage to the outer retina, and again sufficient krypton radiation passed into the choroid to induce blood vessel occlusion, haemorrhage, and oedema. When intraretinal vessels were irradiated, only with argon was sufficient energy absorbed within the vessels to damage them or their surroundings in the inner retina. The implications of these findings are discussed in relation to the therapeutic uses of lasers.

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Section: Secondary Responses To Laser Irradiationmentioning

confidence: 99%

A comparative histopathological study of argon and krypton laser irradiations of the human retina.

Marshall¹,

Bird²

1979

British Journal of Ophthalmology

180

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“…These phenomena are well documented in the literature. [1][2][3][4][5][6][7] In view of the recent interest in the use of cryopexy for the treatment of retinal detachment, the present investigation was undertaken to assess the histologic effect on the vitreous of subfreezing temperatures applied to the sclera. The changes were compared with those which occur with minimally applied Mira diathermy and Zeiss photocoagulation.…”

mentioning

confidence: 99%

Effect of Cryopexy on the Vitreous

Kirkconnell¹,

Rubin²

1965

Archives of Ophthalmology

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“…The authors created an artificial retinal detachment by suction of the vitreous and performed photocoagulation on the RPE cells. Although RPE cells were directly coagulated by this method, the process of wound healing may have been modified by the remaining artificial retinal detachment and photocoagulation [16,21]. RPE cells react to repair retinal damage by dedifferentiation in various pathologic conditions, such as retinal detachment, traumatic injury, and photocoagulation [6,7,18].…”

Section: Discussionmentioning

confidence: 99%