Histopathological Study of Neoplastic and Non-Neoplastic Thyroid Lesions: An Institutional Experience of 2 Years

Dash, Monalisa; Chandrashekhar, K; Raghu, K; Kethireddy, Saadvi

doi:10.14260/jemds/2016/1213

Cited by 9 publications

(12 citation statements)

References 4 publications

(4 reference statements)

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“…Out of the 101 casesthe male to female ratio was 1:7.41 (Males = 12 and Females = 89). A similar finding was noted in a study by Sameer et al [2] andKhadatkar et al [1] where a clear female predominance was observed.…”

Section: Discussionsupporting

confidence: 91%

“…The age-wise distribution among the study population. The maximum number of patients belonged to the age group between 20-50 years, which was also noted in the study by Sameer et al [2] and Khadatkar et al [1].…”

Section: Discussionsupporting

confidence: 77%

“…A unique feature of Thyroid lesions is that both non-neoplastic and neoplastic diseases affect it and lead to diffuse or nodular enlargement. Non-neoplastic lesions are comparatively more common in thyroid like goitre, thyroiditis and graves' disease [1]. Even after much advances in the field of endocrinology, the thyroid gland still remains a subject of keen interest and importance due to the broad spectrum of lesions and presentations [2].…”

Section: Introductionmentioning

confidence: 99%

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Clinical and cytological spectrum of thyroid lesions and the role of fine needle aspiration cytology in its diagnosis at a tertiary care hospital

Patil

Bommanahalli

2019

Trop J Pathol Microbiol

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Background: Thyroid lesions are one of the significant clinical problems encountered in most of patients coming to the tertiary care units. Fine Needle Aspiration Cytology (FNAC) is the present day's worldwide accepted diagnostic tool as it is a cost effective, minimally invasive, low complication, non-operative method and has a high sensitivity and specificity in most of thyroid lesions. Fine Needle Aspiration Cytology can be used in the diagnosis of these lesions and hence categorising them into benign / inflammatory / neoplastic and aiding the clinician in the next step of surgical / medical management and reduces the unwanted surgeries. Aim: To study the clinical and cytological spectrum of thyroid lesions encountered in everyday practice. Materials and Methods: This was a retrospective study conducted over the period of 1 year and 1 month, from January 2018 to January 2019 in department of pathology Gadag Institute Medical Science, Gadag. A total of 101 Patients with thyroid lesions who underwent Fine Needle Aspiration procedure were identified and their clinical details, available biochemical and radiological parameters were collected, and cyto-morphological features were studied. The lesions were categorised into benign, inflammatory, Follicular neoplasm, malignant and inadequate. Results: Out of 101 cases studied, 47 (46.5%) were Benign, 33 (32.6%) were Inflammatory,09 (8.9%) cases were Follicular Neoplasm and 04 (3.9%) cases were Malignant while 09 (8.9%) cases were inadequate. Conclusions: FNAC is one of the simple useful primary diagnostic tool for the identification and categorization of thyroid lesions. It is safe, cost-effective, minimally invasive and sensitive technique for its diagnosis.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 77%

Section: Introductionmentioning

confidence: 99%

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Clinical and cytological spectrum of thyroid lesions and the role of fine needle aspiration cytology in its diagnosis at a tertiary care hospital

Patil

Bommanahalli

2019

Trop J Pathol Microbiol

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“…Diseases of the thyroid are of great importance because most are amenable to medical or surgical management. 6 The reported incidence of both benign and malignant lesions in surgically treated diseases varies widely between different geographical areas of the world. 7 The study included 620 thyroidectomy specimens received during the study period of 2 years.…”

Section: Discussionmentioning

confidence: 99%

Histopathological analysis of thyroid lesions: an institutional experience

Sheela

Sreedevi

2018

Int J Adv Med

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Background: Diseases of thyroid are one of the most common endocrine disorders affecting general population which range from non-neoplastic to neoplastic lesions. The incidence and pattern of thyroid lesions depend on various factors which include sex, age, ethnic and geographical patterns. Majority of thyroid lesions are non-neoplastic only <5% are malignant. The aim of the present study was to determine the frequency and histomorphological pattern of thyroidectomy specimens and their relationship with age and sex of the patient.Methods: This retrospective study was conducted in the department of pathology, Govt. Medical College, Alappuzha for a period of 2 years. The study included 620 thyroidectomy specimens received in the Department of Pathology. All the biopsy reports were reviewed, and different lesions were categorised according to age and gender distribution. The data was analysed by standard statistical methods.Results: The commonest of the non-neoplastic lesions was nodular colloid goiter followed by lymphocytic thyroiditis, Hashimoto thyroiditis Nodular hyperplasia and thyroglossal cyst. Most common malignant lesion in this study is papillary carcinoma and benign lesion is follicular adenoma. Age group of patients ranged from 6 ½ to 84 years. The study showed a female predominance of 88.38%.Conclusions: Thyroid disorders are commonly encountered endocrine diseases. The study showed a female predominance. Peak age of incidence of thyroid lesions was between 40 and 50 years. Most common lesion was follicular adenoma and most common malignant lesion was papillary carcinoma.Histopathological examination is the mainstay for definite diagnosis and management of thyroid neoplasms.

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“…Non-neoplastic lesions are more common in thyroid like goitre, thyroiditis and graves' disease. 1 Neoplastic lesions like follicular neoplasms, papillary carcinoma, and medullary carcinoma though less common may show overlapping clinical features with non-neoplastic lesions. There are various diagnostic modalities to work up thyroid diseases which include thyroid function tests, radioisotope scan, USG, AMA levels and FNAC.…”

Section: Introductionmentioning

confidence: 99%

Cytopathological evaluation of various thyroid lesions based on Bethesda system for reporting thyroid lesions

2017

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Background: An encouragement for the thyroid proposal was the Bethesda system for reporting cervical cytology interpretations, a uniform reporting system for thyroid FNA will facilitate effective communication among health care providers. The objective of the present study was to classify thyroid lesions in various categories under Bethesda system correlating the cytological findings in various thyroid lesions with clinical and radiological details.Methods: A retrospective study on FNAC thyroid was performed in a tertiary hospital and a Medical teaching institution in Mumbai, Maharashtra, India which included cases which were reported from 1st January 2010 to 31st July 2011. For cytomorphological analysis, all smears (Papanicolaou and MGG) were reviewed and cases were categorized into six Bethesda categories. The FNAC findings were correlated with clinical, radiological and laboratory findings. Discrepancies between original diagnosis and review diagnosis as well as difficulties encountered during application of Bethesda were studied in detail.Results: Total 413 FNACs were received during the study period. The original diagnoses included 10 different categories or labels some of which were descriptive. On application of Bethesda, maximum cases were found in category II (82.32%) followed by category I i.e. inadequate (7.7%). Category III (Atypia of Undetermined significance) included wide spectrum of cases which were previously diagnosed as goitre, suspicious or neoplastic.Conclusions: Bethesda system of reporting thyroid FNAC has brought uniformity in cytology reporting. It has facilitated better understanding between cytopathologist and clinicians as every category connotes specific risk of malignancy and recommends treatment.

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Histopathological Study of Neoplastic and Non-Neoplastic Thyroid Lesions: An Institutional Experience of 2 Years

Cited by 9 publications

References 4 publications

Clinical and cytological spectrum of thyroid lesions and the role of fine needle aspiration cytology in its diagnosis at a tertiary care hospital

Clinical and cytological spectrum of thyroid lesions and the role of fine needle aspiration cytology in its diagnosis at a tertiary care hospital

Histopathological analysis of thyroid lesions: an institutional experience

Cytopathological evaluation of various thyroid lesions based on Bethesda system for reporting thyroid lesions

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