Histopathological Pattern of Primary Glomerulonephritis - A Single Center Experience

Abstract

lomerulonephritis is the most common cause of chronic kidney disease in our country like in other developing countries. The incidence and histological pattern of primary GN in our countare is inadequately described. This cross-sectional prospective study was conducted at the nephrology unit in Holy Family Red Crescent Medical College Hospital, a tertiary care teaching hospital in Dhaka, Bangladesh starting from January 2019 - December 2019 including all patients with suspected primary GN who underwent kidney biopsies. Total 35 biopsies were performed. M: F 1.3:1 .Mean age was 33.71+_12.2 yrs. Membranoproliferative GN (34.28%) was the most common cause followed by mesangioproliferative (22.85%), IgA nephropathy (17.14%), membranous (11.42%), FSGS ( 11.42%) and minimal change disease (2.8%). Among 35 cases, 20 had proliferative verity. In immunofluroscence study, 19 had mild to marked deposits of immunoglubulin. 5.71% had post-biopsy complication which was not significant enough. As the sample size was small so needs more studies in large to get the specific epidemiological patterns of primary GN.