Histopathological findings in COVID‐19‐induced cutaneous lesions. Clinicopathological correlation of SARS‐CoV‐19 dermatologic patterns: review of the literature

Abstract

An increasing number of publications have brought attention to COVID‐19‐associated cutaneous lesions. Histopathological descriptions and clinical correlation of the histopathological findings of COVID‐19 skin lesions are lacking. In this manuscript, we reviewed and described the histopathological characteristics of COVID‐19 infection cutaneous patterns reported in the literature.

Pityriasis Lichenoides et Varioliformis Acuta as a Complication of COVID-19 Infection

“…Advanced findings usually encountered in febrile ulceronecrotic Mucha−Habermann disease may show an extension of the inflammatory infiltrate into the epidermis, extravasation of erythrocytes, widespread epidermal necrosis, and nuclear debris in necrotic areas [1,2]. Histopathological examination of our patient showed features such as vacuolar degeneration of the basal layer with necrotic keratinocytes and dense deep periglandular lymphocytic infiltration, which have been consistently described in COVID-19-related dermatosis [20]. Erythematous and erythematous-crusted papules.…”