Histopathological Changes in Liver of Mice after Exper Imental Envenomation with Androctonus Amoreuxi Scorpion Venom

Fetaih, Hamdy; Shoukry, Nahla M.; Soliman, Belal A.; Mohallal, Mahmoud E.; khaled, Howayda S.

doi:10.12816/0006401

Cited by 3 publications

(3 citation statements)

References 4 publications

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“…The patients might die of respiratory paralysis with pulmonary edema within 2 to 3 hours after being sting 133. Fetaih et al (2013) injected experimental mice with scorpion venom 134. They reported most obvious changes in the liver with acute cellular swelling, hydropic degeneration, congestion of central veins and portal blood vessels.…”

Section: Clinical Studies With Different Insectsmentioning

confidence: 99%

A review on Respiratory allergy caused by insects

Kausar¹

2018

Bioinformation

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Hypersensitivity or allergy encompasses a wide range of immunological reactions that generally have adverse consequences involving one or many organ systems of the body. Allergens are usually glycoprotein or chemically complex low molecular weight substances. The common allergens include pollen, fungal spores, house dust mite and house dust, animal danders, drugs, foods, insect emanations, and detritus, etc. Information on the role of insects in respiratory allergy is increasing in the literature. There are about 30 million living species of insects. These insects can broadly be classified as stinging insects, biting insects and non-stinging and non-biting insects. All materials form insets namely wings, scales, saliva; dried feces and venom can cause allergic diseases, such as rhinitis, conjunctivitis, asthma and urticaria. There are wide varieties of insects such as moths, butterflies, bees, wasps, hornets, yellow jackets, flies, beetles, cockroaches, and mosquitoes. Exposure to emanations and detritus of these insects may lead to several allergies in some genetically predisposed individuals. Therefore, it is of interest to review allergies caused by various insect’s stings and bites and their adverse effect on the human body.

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Section: Clinical Studies With Different Insectsmentioning

confidence: 99%

A review on Respiratory allergy caused by insects

Kausar¹

2018

Bioinformation

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“…Besides, the patients may die of respiratory paralysis with pulmonary edema within 2 to 3 hours after being sting (Efrati, 1949). Shoukry and Fetaih et al (2013) injected experimental mice with scorpion venom. They found that the most obvious changes in the liver were acute cellular swelling, hydropic degeneration, congestion of central veins and portal blood vessels.…”

Section: Introductionmentioning

confidence: 99%

A Mini-Review on Skeeter Syndrome or Large Local Allergy to Mosquito Bites

Abdel-Motagaly

Mohamad

Morsy

2017

Journal of the Egyptian Society of Parasitology

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“…There are various physiopathological and pharmacological studies about the species of A. australis, A. crassicauda and A. amoreuxi (e.g. Saidi et al, 2013;Aghabiklooei et al, 2013;Fetaih et al, 2013). However, no information is available about the black fat-tailed scorpion or A. bicolor.…”

Section: Introductionmentioning

confidence: 99%

Cardiac disorders and mode of action of the Egyptian scorpion venom Androctonus bicolor on isolated toad’s heart

Abdel-Rahman

Ayed

Abdel–Mottaleb

et al. 2015

The Journal of Basic & Applied Zoology

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Scorpion venom is a complex mixture of components with various pharmacological and toxicological effects. It is characterized by the presence of a large number of toxins that specifically interact with ion channels of excitable cells. The Egyptian scorpion Androctonus bicolor belongs to the family of Buthidae and until now no information is available about the effect of its venom on cardiac muscles. Using an in vitro approach, cardiotoxicity and mode of action of A. bicolor venom on isolated toad's heart were investigated. Direct application of scorpion venom (0.5 lg/ml) into isolated toad's heart induced a remarkable bradycardia concomitant with a protraction in the conduction time (P-R interval). In the meantime, a significant increase in the R-wave amplitude (ventricular contraction) was noticed after 5 min of venom perfusion. Various cases of cardiac disorders were recorded such as sinus arrhythmias, ectopic beats and different degrees of heart block. Through using different autonomic and ion channel blockers, the possible mechanism of action of A. bicolor venom on isolated toad's heart was revealed. The application of both atropine (4 lg/ml) and verapamil (5 lg/ml) could not alleviate the pronounced negative chronotropic and positive inotropic effects. Meanwhile, a significant decrease in the R-wave amplitude was observed after propranolol (5 lg/ml) application. In conclusion, our findings indicate that the venom of A. bicolor directly influenced the cardiac electrical activity of toads through b-adrenergic receptors. The direct effect of this venom on cardiac tissues may significantly contribute in the development of several cardiotoxic effects following scorpion sting.

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Histopathological Changes in Liver of Mice after Exper Imental Envenomation with Androctonus Amoreuxi Scorpion Venom

Cited by 3 publications

References 4 publications

A review on Respiratory allergy caused by insects

A review on Respiratory allergy caused by insects

A Mini-Review on Skeeter Syndrome or Large Local Allergy to Mosquito Bites

Cardiac disorders and mode of action of the Egyptian scorpion venom Androctonus bicolor on isolated toad’s heart

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