Histopathological alterations induced by marine environmental pollutants on the bivalve Cerastoderma glaucum (Bruguière 1789) from Temsah Lake, Suez Canal, Egypt

Mona, Mohamed H.; El‐Khodary, Gihan M.; Abdel-Halim, Khaled Y.; Omran, Nahla E.; El-Aziz, Karolin K. Abd; El-Saidy, Salwa A.

doi:10.1007/s11356-021-14966-4

Cited by 3 publications

(3 citation statements)

References 69 publications

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“…The suitability of C. glaucum as a model for exposure to pollutants was confirmed by several studies, making it an ideal candidate for experimental studies. However, the defense responses of this bivalve in relation to the pollutants tested were not addressed in these studies [71][72][73].…”

Section: Discussionmentioning

confidence: 99%

Exploring the Internal Defense System of Cerastoderma glaucum (Bruguière, 1789) Exposed to Pristine Microplastics: The Sentinel Role of Haemocytes as Biomarkers

Alesci,

Di Paola,

Marino

et al. 2024

Fishes

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The ubiquitous presence of microplastics (MPs) in the environment is a major concern for the conservation of biodiversity. Numerous studies show the detrimental effects of MPs on marine species, especially because of their small size and their capacity to absorb organic contaminants from their surroundings. The bivalve mollusk Cerastoderma glaucum (Bruguière, 1789), because of its wide geographic distribution and immobile feeding habits, can be used as a sentinel and bioindicator species. By examining the presence, localization, and co-localization of Toll-like receptor 2 (TLR2) and inducible nitric oxide synthetase (iNOS), this study aims to evaluate the response of the internal defense system of C. glaucum to pristine MPs through the employment of confocal microscopy and bioinformatics techniques. The results show haemocytes immunoreactive to the antibodies tested; in particular, a higher number of TLR2-positive haemocytes can be observed in the group exposed to pristine MPs. These findings suggest that haemocytes can play a key biomarker role as sentinels to environmental pollutants. Furthermore, bioinformatics analyses on the antibodies tested confirmed an evolutionary conservation of these molecules. These data highlight the critical role of phagocytosis in identifying ecosystem damage and are helpful in developing biosensors with less negative effects on the environments in which they are applied.

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Section: Discussionmentioning

confidence: 99%

Exploring the Internal Defense System of Cerastoderma glaucum (Bruguière, 1789) Exposed to Pristine Microplastics: The Sentinel Role of Haemocytes as Biomarkers

Alesci,

Di Paola,

Marino

et al. 2024

Fishes

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“…Heavy metal toxicity causes notable histological changes in the vital organs of invertebrates [ 35 , 65 , 66 ]. Mussels’ gills are considered to be sensitive to toxicity because of their crucial role in respiration, food absorption, and extended surface area [ 67 , 68 ]. Fahmy and Sayed [ 33 ] observed gill filament dilation, epithelial lifting, necrosis, hemocyte congestion, hyperplasia, filament deformities, and cilia damage in bivalve Coelatura aegyptiaca exposed to zinc nanoparticles.…”

Section: Discussionmentioning

confidence: 99%

Impact of Pb Toxicity on the Freshwater Pearl Mussel, Lamellidens marginalis: Growth Metrics, Hemocyto-Immunology, and Histological Alterations in Gill, Kidney, and Muscle Tissue

Chowdhury

Schneider

et al. 2023

Toxics

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Pb is one of the most extensively used harmful heavy metals in Bangladesh, and its occurrence in waters affects aquatic organisms significantly. The tropical pearl mussel, Lamellidens marginalis, was exposed to different concentrations (T1 21.93 mgL−1, T2 43.86 mgL−1, and T3 87.72 mgL−1) of Pb(NO3)2 and was evaluated against a control C 0 mgL−1 of Pb(NO3)2, followed by a 96 h acute toxicity test. The LC50 value was recorded as 219.32 mgL−1. The physicochemical parameters were documented regularly for each treatment unit. The values of % SGR, shell weight, soft tissue wet weight, and weight gain remained statistically higher for the control group in comparison with the treatment. No mortality was noted for control units, while a gradually decreased survival rate was recorded for the different treatment groups. Fulton’s condition factor was recorded as highest in the control and lowest in the T3 unit, while the condition indices did not vary between the control and treatment groups. The hemocyte was accounted as maximum in the control and T1, while minimum in T2 and T3. The serum lysosomal parameters also followed a similar pattern, and a significantly low level of lysosomal membrane stability, and serum lysosome activity was noted for T3 and T2 units in comparison to the control group. The histology of the gill, kidney, and muscle was well structured in the control group, while distinct pathologies were observed in the gill, kidney, and muscle tissue of different treatment groups. The quantitative comparison revealed that the intensity of pathological alteration increased as the dosage of Pb increased. The current study, therefore, indicated that intrusion of Pb(NO3)2 in the living medium significantly alters growth performance and hemocyte counts, and chronic toxicity induces histomorphological abnormalities in vital organs.

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“…We present a special section on biological models of bivalve species because, despite their ecological and economic relevance, data on bioaccumulation and contamination risks are lacking in terms of the consumption of certain edible bivalve species. Bivalves are considered one of the main matrices consumed by coastal communities worldwide and are classified as hyperaccumulators of pollutants (Mona et al, 2022). Studies using these biological models will help establish the risks associated with exposure to nonylphenol and its isomers and the appropriate consumer safety guidelines.…”

Section: Bivalves As a Biological Modelmentioning

confidence: 99%

Studies of Endocrine Disruptors: Nonylphenol and Isomers in Biological Models

Parra-Guerra

Acevedo-Barrios

2023

Enviro Toxic and Chemistry

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Certain emerging pollutants are among the most widely used chemicals globally, causing widespread concern in relation to their use in products devoted to cleaniness and asepsis. Nonylphenol ethoxylate (NPEOn) is one such contaminant, along with its degradation product, nonylphenol, an active ingredient presents in nonionic surfactants used as herbicides, cosmetics, paints, plastics, disinfectants, and detergents. These chemicals and their metabolites are commonly found in environmental matrices. Nonylphenol and NPEOn, used, are particularly concerning, given their role as endocrine disruptors chemical and possible neurotoxic effects recorded in several biological models, primarily aquatic organisms. Limiting and detecting these compounds remain of paramount importance. The objective of the present review was to evaluate the toxic effects of nonylphenol and NPEOn in different biological models.

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Histopathological alterations induced by marine environmental pollutants on the bivalve Cerastoderma glaucum (Bruguière 1789) from Temsah Lake, Suez Canal, Egypt

Cited by 3 publications

References 69 publications

Exploring the Internal Defense System of Cerastoderma glaucum (Bruguière, 1789) Exposed to Pristine Microplastics: The Sentinel Role of Haemocytes as Biomarkers

Exploring the Internal Defense System of Cerastoderma glaucum (Bruguière, 1789) Exposed to Pristine Microplastics: The Sentinel Role of Haemocytes as Biomarkers

Impact of Pb Toxicity on the Freshwater Pearl Mussel, Lamellidens marginalis: Growth Metrics, Hemocyto-Immunology, and Histological Alterations in Gill, Kidney, and Muscle Tissue

Studies of Endocrine Disruptors: Nonylphenol and Isomers in Biological Models

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