Histomorphometric study of trabecular channels in normal iliac bone

Satô, Kôzô; Wakamatsu, Eikichi; Sato, Takatoshi; Honma, Tetsuro; Kotake, Hidetoshi; Byers, Paul D.

doi:10.1007/bf02555733

Cited by 18 publications

(19 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The obvious mechanism for this prevalence is tunneling resorption from the trabecular surface with subsequent circumferential osteoid deposition on the surfaces. The significant correlation of the number of osteons with the trabecular width and the higher prevalence in more massive structures reconfirmed our earlier study (Sato et al 1986), suggesting that the osteons are formed so as to meet the metabolic need of thickened trabeculae by extending the surface available for remodeling and gas exchange with the blood flow within the canal. But we postulate an additional significance for this phenomenon: it compensates for the loss of surface available for resorption as the result of increased osteoid coverage (Sato and Byers 1981).…”

Section: Resultssupporting

confidence: 83%

“…Thirty-five biopsies, taken during either the treatment for coxarthrosis with total hip replacement, surgical decompression with spinal fusion for cervical and lumbar spondylosis, or osteosynthesis for femoral neck fracture, were from patients who were otherwise fit, ambulatory, and free from metabolic bone disease as proved by laboratory examinations. Six specimens were taken during autopsies from cases of sudden death (Sato et al 1986). …”

Section: Methodsmentioning

confidence: 99%

“…The feature which positively identifies a cavity as an osteon is the circumferential lamellar pattern of the mural tissue, bone or osteoid (Sato et al 1986). These were ascribed to Class A (Fig.…”

Section: The Classification Of Intratrabecular Cavities and Osteonsmentioning

confidence: 99%

“…The dissecting resorption cavities are tunneling and hook varieties, and are defined elsewhere (Sato and Byers 1981). The criterion to select the osteons from those cavities was based on the mean external diameter of 84 Class A osteons in normal bone (Sato et al 1986). Any Class B cavity whose diameter was less than this mean ±s.D, was regarded as an osteon, but qualified as Class B.…”

Section: The Classification Of Intratrabecular Cavities and Osteonsmentioning

confidence: 99%

See 3 more Smart Citations

Histomorphometric Study of Intratrabecular Osteons in the Iliac Bone in Three Metabolic Bone Diseases.

Satô

Byers

1994

Tohoku J. Exp. Med.

Self Cite

View full text Add to dashboard Cite

Full-thickness biopsy specimens of iliac bones were submitted to morphometric analysis of intratrabecular osteons to study whether and how much the number and density of osteons increase in some metabolic bone diseases such as osteomalacia (OM), primary hyperparathyroidism (PHPT) and renal osteodystrophy (ROD). The biopsies were taken from 16 patients with OM of various causes, 18 with PHPT, 12 with ROD, and from 41 control cases. All the specimens were methacrylate-embedded, sectioned undecalcified and stained with solochrome cyanine or HE. Morphometry included measurements of the density of osteons and the volume of bone and osteoid, partially assisted with a semiautomatic digital image analyzer. Intratrabecular osteons were found to be more numerous in patients with metabolic disorder than in control. It was shown by discriminant analysis that the elevated number of osteons/cm2 tissue area contributes to the differentiation of abnormal from normal bones. The presence of blood vessels in the osteons indicated the biological significance of osteon formation which extends the metabolic surface of trabeculae, providing a basis for trabecular hypertrophy. intratrabecular osteons; metabolic bone disease; tunneling resorption; iliac bone; histomorphometry Intratrabecular resorption cavities and osteons have been the subject of several studies (Jaffe

show abstract

Section: Resultssupporting

confidence: 83%

Section: Methodsmentioning

confidence: 99%

Section: The Classification Of Intratrabecular Cavities and Osteonsmentioning

confidence: 99%

Section: The Classification Of Intratrabecular Cavities and Osteonsmentioning

confidence: 99%

See 2 more Smart Citations

Histomorphometric Study of Intratrabecular Osteons in the Iliac Bone in Three Metabolic Bone Diseases.

Satô

Byers

1994

Tohoku J. Exp. Med.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Similarly, material composition also plays a significant role in the process [1][2][3][4][5][6][7]. Thus most research into bone grafting has focused on duplicating the structure and material of cancellous bone using natural and synthetic structures.…”

Section: Introductionmentioning

confidence: 99%

A quantitative technique for comparing synthetic porous hydroxyapatite structures and cancellous bone

O’Kelly

Tancred

McCormack

et al. 1996

J Mater Sci: Mater Med

View full text Add to dashboard Cite

There are many different materials currently available for cancellous bone grafting. There is however, very little information relating the morphology of these materials to cancellous bone. Work was undertaken to develop a quantitative method for comparing synthetic hydroxyapatite bone structures with cancellous bone. The bases for comparison were mean plate thickness, mean plate distance, mineral area fraction, mineral volume fraction and plate orientation coupled with mechanical tests. The aim of this work was to develop a protocol for assessing whether these critical parameters which influence the success of bone implants were achieved in the synthetic materials. The methodology is successful in providing quantitative information about the mineral area fraction, the mean plate distance or pore size and the intercept frequency as a function of angle. Combining these three provides a quantitative measure of how much mineral there is and how it is distributed and oriented. The mechanical tests yield strengths and moduli values based on apparent density. The results of the mechanical tests can also be plotted as functions of the more discrete structural features such as those quantified in the image analysis to allow for even more equitable and systematic comparisons of different porous materials.

show abstract

The developing juvenile ischium: Macro‐radiographic insights

2014

View full text Add to dashboard Cite

Despite the importance of the human pelvis as a weight-bearing structure, there is a paucity of literature that discusses the development of the juvenile innominate from a biomechanical perspective. This study aims to add to the limited body of literature pertaining to this topic through the qualitative analysis of the gross architecture of the human ischium during the juvenile period. Macro-radiographs of 55 human ischia ranging from 28 intra-uterine weeks to 14 years of age were examined using intensity-gradient color mapping to highlight changes in gross structural morphology with increasing age. A clear pattern of maturation was observed in the juvenile ischium with increasing age. The acetabular component and ramus of the ischium consistently displayed low bone intensity in the postnatal skeletal material. Conversely the posterior body of the ischium, and in particular the ischial spine and lesser sciatic notch, exhibited increasing bone intensity which first arose at 1-2 years of age and became more expansive in older cohorts. The intensity patterns observed within the developing juvenile ischium are indicative of the potential factors influencing the maturation of this skeletal element. While the low intensity acetabular fossa indicates a lack of significant biomechanical interactions, the posterior increase in bone intensity may be related to the load-bearing nature of the posterior ischium.

show abstract

Histomorphometric study of trabecular channels in normal iliac bone

Cited by 18 publications

References 4 publications

Histomorphometric Study of Intratrabecular Osteons in the Iliac Bone in Three Metabolic Bone Diseases.

Histomorphometric Study of Intratrabecular Osteons in the Iliac Bone in Three Metabolic Bone Diseases.

A quantitative technique for comparing synthetic porous hydroxyapatite structures and cancellous bone

The developing juvenile ischium: Macro‐radiographic insights

Contact Info

Product

Resources

About