Histomorphometric study of the canine prostate during ageing and in cases of benign prostate hyperplasia

Juodžiukynienė, Nomeda; Aniulienė, Albina

doi:10.1515/jvetres-2016-0013

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“…Routine histological examinations of the prostate gland of dogs affected with BPH showed fibrosis, prominent cystic acini ( Figure-1 ), hyperplasia of acinar epithelium, and concentric laminated concretions of secretory product in acini which corroborated with the reports of earlier workers [ 1 , 4 , 15 ].…”

Section: Resultssupporting

confidence: 89%

Hemato-biochemical alterations and urinalysis in dogs suffering from benign prostatic hyperplasia

Das¹,

Patra²,

Das³

et al. 2017

Vet World

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Aim:The study was designed to evaluate the hemato-biochemical alterations, urinalysis along with histomorphological and histological changes of prostate glands in dogs affected with benign prostatic hyperplasia (BPH) in and around Bhubaneswar, Odisha, India.Materials and Methods:In toto, 445 dogs presented to the Teaching Veterinary Clinical Complex of the College of Veterinary Sciences and Animal Husbandry, one Government Veterinary Hospital and two pet clinics in and around Bhubaneswar screened for the presence of BPH. Most of the 57 dogs were 6 years and above as reported by the owners. Only 57 dogs found positive for BPH basing on the presence of typical clinical signs subjected for a detailed hemato-biochemical study. Most of the 57 dogs were 6 years and above as reported by the owners. Routine and microscopic urinalyses were done as per the routine procedure. Histomorphological evaluations of prostate glands were done through manual rectal palpation. Histological examinations of prostate tissue sections of two dead dogs were conducted with routine hematoxylin and eosin stain.Results:The study revealed about 12.8% (57/445) of dogs was suffering from BPH. Typical clinical signs - such as passing small thin tape-shaped feces, holding tail away from backward, tenesmus, and straining during urination and defecation - were seen in most of the cases. Urine samples of affected dogs were positive for glucose, occult blood, and protein. A significant decrease in lymphocytes and increase in eosinophil counts in dogs with BPH was recorded. Serum biochemical analysis showed a nonsignificant increase in creatinine and blood urea nitrogen with a significant decrease in total protein, albumin, globulin, A:G ratio. Histology of prostate glands collected during postmortem was characterized by fibrosis of prostate gland, and hyperplasia of the acinar epithelium.Conclusions:High rate of the prevalence of BPH in dogs poses an alarming condition which if diagnosed at an early stage can certainly prolong the longevity of the dogs.

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Section: Resultssupporting

confidence: 89%