1978
DOI: 10.1136/bjo.62.1.53
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Histology of spheroidal degeneration of the cornea in Labrador.

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1986
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Cited by 43 publications
(20 citation statements)
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“…Climatic droplet keratopathy is relatively unusual and more often reported in harsh climates, such as arctic or desert areas (Klintworth 1977). Ultraviolet radiation is thought to play a role in its etiology (Taylor 1980;Johnson & Ghosh 1975;Johnson & Overall 1978;Dahan et al 1986;Clear et al 1979). Recently, climatic proteoglycan stromal keratopathy in the Middle East has been described by Waring et al (1995).…”
Section: Discussionmentioning
confidence: 99%
“…Climatic droplet keratopathy is relatively unusual and more often reported in harsh climates, such as arctic or desert areas (Klintworth 1977). Ultraviolet radiation is thought to play a role in its etiology (Taylor 1980;Johnson & Ghosh 1975;Johnson & Overall 1978;Dahan et al 1986;Clear et al 1979). Recently, climatic proteoglycan stromal keratopathy in the Middle East has been described by Waring et al (1995).…”
Section: Discussionmentioning
confidence: 99%
“…The latter may be of altered plasma constituents from leaking limbal vessels. 22 The accepted theories of collagen degeneration in both lattice dystrophy and corneal elastosis suggest the possibility of a closely related metabolic reason for both, although one is genetically inherited and the other is not. Corneal elastosis may be associated with a variety of chronic ocular and corneal disorders.7" Our patients presented clinical findings or a history of other corneal diseases like those of other cases with corneal elastosis.…”
Section: Discussionmentioning
confidence: 99%
“…The coalescence and increased volume of these spherules or deposits may cause disruption of Bowman’s membrane and elevation and thinning of the corneal epithelium [1,8,9,10]. Electron microscopy has shown that globules are round, electron-dense and sharply demarcated structures, always surrounded by basement membrane material, and adjacent disorganized collagen fibrils [1,9]. The droplets generally lack positive staining for fat or calcium [1].…”
Section: Introductionmentioning
confidence: 99%
“…The droplets generally lack positive staining for fat or calcium [1]. Although the exact nature and composition of droplets remain unclear, proteinaceous constituents have been found [8,9,10,11]. …”
Section: Introductionmentioning
confidence: 99%