Histology after tonsillectomy?

Schröck, Andreas; Jakob, Mark; Send, Thorsten; Heukamp, Lukas C.; Bücheler, M.; Bootz, Friedrich

doi:10.1007/s00106-009-1889-0

Cited by 9 publications

(16 citation statements)

References 20 publications

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“…One of these patients presented with PTA and another had a history of recurrent PTA [3]. In agreement with other researchers, the possibility of PTA as an independent risk factor for tonsillar malignancy was questioned [1,3,10]. A literature search revealed several case reports on tonsillar malignancy presenting as PTA, which supported the concept that PTA may be associated with tonsillar malignancy [5][6][7][8][9][10][12][13][14].…”

Section: Introductionmentioning

confidence: 60%

“…In 2009, Schrock et al published a series of 1,523 routine tonsillectomy patients (including 51 patients with PTA) and identified two with unsuspected malignancy, one of these had a history of recurrent PTA (a 62-year-old male, diagnosed with lymphoma). They concluded that prior PTA should be added to the list of risk factors [1]. In 1965, Weibel reviewed 68 patients with manifest tonsillar malignancy.…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of unsuspected tonsillar malignancy in routine tonsillectomy specimens (adults and children) is low (0.011-0.015 %) [1][2][3]. Clinical risk factors, which indicate histological examination of tonsillectomy specimens, have been defined and discussed in previous publications [1][2][3][4].…”

Section: Introductionmentioning

confidence: 98%

“…Clinical risk factors, which indicate histological examination of tonsillectomy specimens, have been defined and discussed in previous publications [1][2][3][4]. These risk factors include: (1) history or diagnosis of cancer, (2) tonsillar asymmetry, (3) palpable firmness or visible lesions of the tonsils, (4) concomitant neck adenopathy, (5) unexpected weight loss and (6) constitutional symptoms (fatigue, night sweats, fever and anorexia).…”

Section: Introductionmentioning

confidence: 99%

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Tonsillar malignancy in adult patients with peritonsillar abscess: retrospective study of 275 patients and review of the literature

Rokkjær

Klug

2014

Eur Arch Otorhinolaryngol

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Unsuspected tonsillar malignancy in routine tonsillectomy specimens is rare. A potentially increased risk of unsuspected tonsillar malignancy in adult patients presenting with peritonsillar abscess (PTA) was noted in a recent review. Furthermore, a literature search revealed several case reports concerning tonsillar malignancy presenting as PTA. Thus, the aim of the current study was to explore the prevalence of tonsillar malignancy in adult patients with PTA. A retrospective review of all adult patients undergoing tonsillectomy due to PTA from January 2001 to December 2012 at the Ear-Nose-Throat Department was performed. In 275 consecutive adult patients with PTA (median age 40 years, range 30-89 years), we identified one patient with unsuspected tonsillar malignancy (prevalence 0.3 %); a 40-year-old, previously healthy, male was diagnosed with acute myeloid leukaemia. Reviewing the literature, we identified 13 cases of tonsillar malignancy presenting as PTA (median age 49 years, range 2-66 years). Our data represents the only series of histological examined tonsillectomy specimens from PTA patients reported in the literature. We identified one case of unsuspected tonsillar malignancy in this relatively small series. We find it important to stress, that we had no knowledge of this patient before designing the study. Hence, the prevalence of 0.3 % is unbiased in this respect. More, and preferably, larger studies are needed to determine the prevalence with greater certainty. At present, no definitive conclusions can be made, but clinicians should be aware that PTA infrequently masquerade tonsillar malignancy.

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Section: Introductionmentioning

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

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Tonsillar malignancy in adult patients with peritonsillar abscess: retrospective study of 275 patients and review of the literature

Rokkjær

Klug

2014

Eur Arch Otorhinolaryngol

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“…Literatürde, histopatolojik incelemenin gerekliliği konusunda yaştan ziyade preoperatif maligniteyi düşündürecek bulguların varlığının daha önemli olduğu görüşü savunulmaktadır. [15][16][17] Beaty ve ark., erişkin tonsillerinde maligniteyi düşündürecek risk faktörlerini araştırmak için yaptıkları bir çalışmada; kanser öyküsü, tonsil yüzeyinde ülseratif lezyon, asimetrik hipertrofi, tonsillerde sertlik, boyunda lenfadenopati ve kilo kaybı gibi bulguların tonsil malignitesini düşündürebilecek risk faktörleri olduğunu belirtmişlerdir. 15 Maligniteyle karşılaşılan hastaların büyük kısmında bu risk faktörlerinden iki veya daha fazlasının olduğunu göstermişlerdir.…”

Section: Discussionunclassified

The Retrospective Analysis of Tonsillectomy Specimens and the Importance of Histopathological Examination

Eroğlu¹,

Keleş²,

Karlıdağ³

et al. 2018

KBB ve BBC Dergisi

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ulak-burun ve boğaz (KBB) cerrahlarının en sık yaptığı operasyonlar arasında yer alan tonsillektomi ve/veya adenoidektomi, Amerika Birleşik Devletleri'nde yılda 400.000'den fazla uygulanmaktadır. 1 Çocukluk yaş grubunda tonsillektomi endikasyonlarının büyük bir kısmını obstrüksiyona bağlı horlama, apne ve yutma güçlüğü oluşturmaktadır. Bu endikasyonu sık geçirilen tonsil enfeksiyonu takip etmektedir. 2 Primer tonsil maligniteleri en sık yassı hücreli karsinomlar (%75), ikinci sıklıkta lenfomalardır ve tüm malignitelerin %2'sini oluşturmaktadır. Tonsil lenfomaları tüm baş-boyun bölgesi lenfomalarının %2-3'ünü oluşturmaktadır. 3 1 1 1 Tonsillektomi Spesmenlerinin Retrospektif Analizi ve Histopatolojik İncelemenin Önemi Ö ÖZ ZE ET T A Am ma aç ç: : Bu çalışmada, tonsillektomi spesmenlerinin rutin histopatolojik incelemesinin gerekliliği literatür bilgileri eşliğinde tartışılmıştır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Çalışmamızda, Temmuz 2008-Ocak 2017 tarihleri arasında Fırat Üniversitesi Hastanesi Kulak Burun Boğaz Kliniği'nde tonsillektomi ve/veya adenotonsillektomi yapılan 1.152 hastanın dosyası yaş, cinsiyet ve histopatolojik sonuçları bakımından incelendi. B Bu ul lg gu ul la ar r: : Çalışmamızda tonsillektomi ve/veya adenotonsillektomi yapılan 1.152 hastanın 18'i malignite şüphesi ile opere edilmiş idi. Geriye kalan 1.134 hastada beklenmedik malignite ile karşılaşılmadı. S So on nu uç ç: : Tonsillektomi spesmenlerinde beklenmedik malignite oranının oldukça düşük olması nedeni ile histopatolojik incelemenin rutin olarak yapılması yerine, preoperatif muayenenin daha dikkatli yapılması gerekmektedir. Fizik muayenede tonsiller asimetri, sertlik, tonsil mukozasında ülserasyon veya boyunda palpabl lenf nodu bulgularından en az biri olan hastalarda, spesmenlerin histopatolojik incelenmesinin daha doğru olduğu düşünülmektedir. A An na ah ht ta ar r K Ke el li im me el le er r: : Tonsillektomi; histopatoloji; malignite A AB BS ST TR RA AC CT T O Ob bj je ec ct ti iv ve e: : In this study, the necessity of routine histopathologic examination of tonsillectomy specimens was discussed in the context of literature. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : In our study, the data of 1.152 patients who underwent tonsillectomy and/or adenotonsillectomy at Fırat University Department of Otorhinolaryngology between July 2008-January 2017 were reviewed for age, sex and histopathologic results. R Re es su ul lt ts s: : Only 18 of 1.152 patients underwent tonsillectomy and/or adenotonsillectomy with the possibility of malignancy. Unexpected malignancy was not encountered in the remaining 1.134 patients. C Co on nc cl lu us si io on n: : Because the rate of unexpected malignancy is very low in tonsillectomy specimens, it is necessary to perform preoperative examination more carefully than histopathologic examination routinely. We think that the histopathological examination of specimens is more accurate in patients with at least one of the symptoms of tonsil asymmetry, hardness, ulceration of the...

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MundhÖHle, Pharynx

Deitmer¹

2009

Handbuch HNO 2009

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Histology after tonsillectomy?

Cited by 9 publications

References 20 publications

Tonsillar malignancy in adult patients with peritonsillar abscess: retrospective study of 275 patients and review of the literature

Tonsillar malignancy in adult patients with peritonsillar abscess: retrospective study of 275 patients and review of the literature

The Retrospective Analysis of Tonsillectomy Specimens and the Importance of Histopathological Examination

MundhÖHle, Pharynx

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