Schwannomas are benign tumors arising from schwann cells in peripheral, cranial, and autonomic nerve sheaths. Approximately half of all cases of schwannomas are observed in the head and neck region. In this study, a 71-year-old male patient presenting with a stiff mobile mass in the left supraclavicular region and diagnosed as a schwannoma after total excision was presented.
Otitis media with effusion (OME) is fluid accumulation in the middle ear without signs of systemic infection. OME can cause hearing loss, ear fullness, speech retardation, and a decrease in social relations and school success. In the treatment of OME, methods such as medical treatment and placing a tympanostomy tube in the eardrum are used. Correct evaluation of the eardrum is necessary to diagnose OME and follow‐up properly in the following period. In this study, we aimed to evaluate the otoendoscopic images of the eardrum in patients with otitis media with effusion using deep models. In the proposed model, Efficientnetb0, Darknet53, and Densenet201 architectures are used as the base. The feature maps obtained using these architectures are combined. In this way, different features of the otoendoscopic images of the eardrum in the data set were extracted and combined using different architectures. neighborhood component analysis optimization technique is used to select important features from the combined feature maps. By using this optimization method, the size of feature maps is reduced. In this way, the model is trained faster, and the testing process is carried out in a shorter time. When these features are classified in different classifiers, the model we propose has the most successful average accuracy value of 94.27% in the SVM classifier.
Pleomorphic adenoma is a slow-growing salivary gland tumor frequently arising from the parotid gland. In this study, we investigated the role of the insulin-like growth factor I-II receptor (IGFI-IIR) levels on the development of parotid gland pleomorphic adenomas. The study included 20 males and 20 females who had superficial parotidectomy with a histopathological diagnosis of pleomorphic adenoma in Fırat University Otorhinolaryngology Clinic between 2000 and 2011. The ages of the patients ranged between 20 and 50 years. The control tissues were obtained unilaterally from the parotid glands of five female and five male cadavers during autopsy, and consisted of 0.5 × 0.5 cm sized normal parotid gland tissues. The expression of IGFI-IIR were measured in both tumor and tumor-free normal parotid tissue in the study group while only the normal parotid tissues were studied in the cadavers. Primary polyclonal antibodies against IGFI-IIR were used with "Streptavidin-Biotin Complex" method for immunohistochemical staining of both the study and the control groups' tissue sections. In this study, the IGFI-IIR levels were found significantly higher in the pleomorphic adenoma tissue (p < 0.05). In addition, IGFI-IIR expression was greater in normal parotid tissues of the study group when compared to the normal parotid tissues of the cadavers. However, the difference was not statistically significant (p > 0.017). Greater expression for IGFI-IIR in pleomorphic adenoma when compared to normal parotid tissues of the patients and the cadavers suggests that IGFI-II may be important factors in the development of pleomorphic adenoma.
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