Histological evaluation of Curcuma longa–ghee formulation and hyaluronic acid on gingival healing in dog

Enhancement of Periodontal Healing by Application of a Novel Ointment Compared with Hyaluronic Acid, Histological Observation in Animal Model

“…In the present work, we have also observed that surgical sites treated with HA showed more intense inflammatory response compared with GC material two weeks following surgery suggesting a relatively poor basis for immigration of fibroblast and deposition of ECM lead to delay of the repair stage of healing. However, this result agrees with those we obtained in our recent research [11]. In addition, Davidson et al suggested that the hyaluronate-treated wounds tended to accumulate collagen more slowly, which may reflect the capacity of these compounds to modify scarring process [26]; however, these results agree with finding of Min et al showed that the application of HA may reduce scar formation whereas reduced TGF-β1 in the healing tissue which could explained the significant lower repair parameters particularly collagen density of periodontal wounds regions which HA has been applied compared with our novel ointment at the end of second week [27].…”

“…Besides the relatively beneficial effects of biomaterials which contain hyaluronic acid, it has several disadvantages such as complex procedure needed to be prepared, unavailability and its very high cost. Thus, we made a novel ointment entitled Curcuma longa-Ghee formulation or "CG" based on natural constituents; however, the histological finding of our recent research demonstrated that the local application of this new formulation on gingival wound sites significantly accelerated the healing process in comparison with hyluronic acid [11].…”

The Synthesis and Investigation of Swelling Hydrogels Composite Filling by Gelatin

“…Зокрема це: утримання вологи у грунтах, доставка ліків, пов'язки на ранах, які забезпечують абсорбцію, послаблення та знищення некротичної та фібротичної тканини. Також такі гідрогелеві композити можуть бути використані при одержанні гідрогелевих пов'язок та медичних імплантатів [7][8].…”

Desenvolvimento de filmes de desintegração oral incorporados com os extratos de erva baleeira (Cordia verbenácea) e cúrcuma (Curcuma longa)

“…A Curcuma longa tem sido utilizada na medicina tradicional asiática como um tônico estomacal e purificador do sangue, e também para o tratamento de doenças do fígado, da pele e cicatrização de feridas (HABIBOALLAH et al, 2008;SINGH et al, 2010). Entre as ervas, classificadas como especiarias, a cúrcuma é uma das mais pesquisadas devido às suas propriedades farmacológicas (HABIBOALLAH et al, 2008), sendo considerada potencialmente benéfica para o tratamento ou redução de sintomas associados a uma ampla variedade de problemas de saúde, devido a suas propriedades antimicrobiana, anti-tumoral, anti-inflamatória e antioxidante (ANAND et al, 2008;HABIBOALLAH et al, 2008).…”

“…Entre as ervas, classificadas como especiarias, a cúrcuma é uma das mais pesquisadas devido às suas propriedades farmacológicas (HABIBOALLAH et al, 2008), sendo considerada potencialmente benéfica para o tratamento ou redução de sintomas associados a uma ampla variedade de problemas de saúde, devido a suas propriedades antimicrobiana, anti-tumoral, anti-inflamatória e antioxidante (ANAND et al, 2008;HABIBOALLAH et al, 2008).…”