Objectives: The early healing of the periodontal wound in oral cavity may be critical to the treatment outcome. Thus, we made a novel ointment based on natural constituents that our recent investigation suggested a positive therapeutic effects on gingival wounds. The present study was conducted to evaluate the role of this novel biomaterial on periodontal wound healing including soft as well as hard tissue. Materials and Methods: Experimental periodontitis was induced by wire tied around the cement-enamel junction of I 2 , P 1 , P 3 and M 1 in six adult, healthy beagle dogs. After 3 months, mucoperiostal flap elevated and root surfaced was thoroughly scaled and planed. Randomly, three materials including our ointment with two different ratios including materials A and B and hyluronic acid were applied topically and then the flaps were repositioned and sutured. Three dogs at day 7 and the three remaining ones two weeks post-surgery were sacrificed and histological changes were monitored. Results: The result of this study showed that the local appli-* Corresponding author. G. Habiboallah et al. 72 plete healing two weeks post operatively. Conclusion: Our novel material appeared to have outstanding effect on periodontal wound healing which can improve the periodontal healing consequences and provide better strength of periodontal wound flap. From a clinical standpoint, it could play an important role for better repair in diabetic patients who frequently present difficulties in mucosal and cutanous wound healing.
We defend Laurence Nemirow's and David Lewis's Ability Hypothesis against Paul Raymont's criticisms in defense of Jackson's Knowledge Argument. According to the Ability Hypothesis, what Mary lacked when she was in her black-and-white room was a set of abilities; she did not know how to recognize or imagine certain types of experience. Her subsequent discovery of what it is like to experience color amounts to no more than her acquiring these abilities. Appealing to the Molyneux test, Raymont has argued that knowledge of what an experience is like cannot be equated with the possession of any set of abilities, since one can be in possession of a recognitional ability concerning a certain type of experience without knowing what that experience is like. We argue that the intermodal recognitional ability in the Molyneux test and similar ones depends on previous experience and thus makes an implicit appeal to knowledge of what it is like.
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