Histological Assessment of the Effect of Laser Irradiation on Skin Wound Healing in Rats

Abstract

LLLT at 670 nm positively influences all phases of rat skin wound healing.

Clinical evaluation of the efficiency of low-level laser therapy for oral lichen planus: a prospective case series

“…Low-Level Laser Therapy (LLLT) is an approach increasingly used in medicine, which has potential biostimulating effects also if applied to oral tissues by improving wound healing, enhancing epithelization after periodontal surgery, and preventing or healing induced oral mucositis [4][5][6]. Laser biostimulation can obtain different intracellular biological reactions to stimulate regenerative abilities, without undesired adverse effects, reducing also the pharmacological support and its possible invasiveness.…”

Low-Level Laser Therapy is More Effective Than Pulse Ultrasound Treatment on Wound Healing: Comperative Experimental Study

“…13 Simi larly, in many ot her pub lis hed pa pers this be nefi ci al ef fect was ob ser ved bet we en the 5 th and 10th days. 22,27 Our fin ding is in ag re e ment with Bisht et al and ot hers. In this pe ri od, an gi o ge ne sis was found to be slightly hig her in la ser gro up.…”

“…Alt ho ugh it not al ways easy to strictly se pa ra te the se thre e pha ses from each ot her, the inf lam matory pha se mostly ta kes part du ring the first fi ve days, ho we ver it was shown con ti nu e for 15 days. 27,28 The pro li fe ra tory pha se ge ne rally oc curs on 7 th to 15 th days and then the ma tu ra ti on pha se ta kes pla ce. 27,28 Our ex pe ri men tal mo del con sis ted of a cir cu lar wo und inf lic ted bi la te rally on the dorsum of the rats.…”

“…27,28 The pro li fe ra tory pha se ge ne rally oc curs on 7 th to 15 th days and then the ma tu ra ti on pha se ta kes pla ce. 27,28 Our ex pe ri men tal mo del con sis ted of a cir cu lar wo und inf lic ted bi la te rally on the dorsum of the rats. When so me o ne ta kes in to con side ra ti on that pres su re ul cers are ge ne rally cir cu lar rat her than li ne ar, it ap pe ars that our ex pe ri men tal mo del is mo re ap prop ri a te to in ves ti ga te and to adapt the ef fects of dif fe rent the ra pe u tic mo da li ties to cli ni cal prac ti ce.…”

“…13,14,33 In a re cent study, Gal et al ha ve shown that la ser sti mu la ti on shor te ned the inf lam ma tory pha se and ac ce le ra ted the pro li fe ra ti on and ma tu ra ti on pha ses. 27 The se inves ti ga tors al so ob ser ved that LLLT po si ti vely sti mu la ted the re ge ne ra ti on of in ju red epi der mis and re pa ir ment of in ju red musc le and conc lu ded that LLLT po si ti vely inf lu en ces all pha ses of rat skin hea ling. In the pre sent study, la ser app li ca ti on sig nifi cantly in cre a sed fib rob last and col la gen com posi ti on on the 7 th day.…”