Histological and immunohistochemical study on the effect of passive smoking on the skin of adult male albino rats and the possible protective role of nigella sativa oil

Khalaf, Gehan; Mostafa, Hany K.K.

doi:10.1097/01.ehx.0000410719.45416.6f

Cited by 3 publications

(3 citation statements)

References 12 publications

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“…The cigarette smoke was used five lit of the KRC by using a smoking machine for 15 minutes and exposing the rats to the cigarette smoke for five minutes, then the rats were rested to 10 minutes and ventilation by removing the box cover. This operation was repeated five times a day for 4 weeks, where the rats were exposed to the KRC for 6 days in a week [17], [18]. Group 4: The protective group (LSH + KRC), rats were given the LSH (100mg/kg b.w./d.)…”

Section: Animalsmentioning

confidence: 99%

Effect of Libyan Sidr honey on thyroid gland damage induced by cigarette smoke in male rats.

Alshailabi,

Al-Zail,

Darwesh

2023

JOPAS

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The toxicity of cigarette smoke (CS) products is through vast production of reactive oxygen species. So, this study aimed to evaluation the effect of Libyan Sidr honey on thyroid gland damage induced cigarette smoke in male rats. 28 adult male rats were divided into four groups; Group 1: Control group (NC); group 2: rats were received the Libyan Sidr honey (LSH) orally (100 mg/kg b.w./d.) for 4 w.; group 3: rats were exposed to 5 lit of the Karelia red cigarette smoke (KRC) (5 times/d.) by a machine smoking for 4 w.; and group 4: (LSH+KRC) rats were received the LSH orally (100 mg/kg b.w./d.) for 2 w., then the rats were exposed to the KRC generated by a machine smoking for 4 w. with the continuation of LSH doses. The result revealed that T4 showed, non-significant decrease in the KRC group compared to the NC group. While, it was significant declining in T3 with a significant increase in TSH levels as compared to NC group. Moreover, the (LSH+KRC) group showed a noticeable improvement in T4 & T3 as compared with the KRC group. Furthermore, the (LSH + KRC) group showed a significantly positive change in TSH as compared with KRC group. The histopathological examination of the thyroid of rats after exposure to KRC alone showed different histopathological changes when compared with control group. Whereas, the (LSH + KRC) group showed, improve thyroid arrangement with normal thyroid follicles when compared with KRC group. Conclusion, results indicate that the Libyan Sidr honey antioxidant activity against thyroid tissues damage induced cigarette smoke in adult male albino rats.

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Section: Animalsmentioning

confidence: 99%

Effect of Libyan Sidr honey on thyroid gland damage induced by cigarette smoke in male rats.

Alshailabi,

Al-Zail,

Darwesh

2023

JOPAS

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“…As regard the integumentary system, the stratum basale in the skin is the stem cell of the epidermis, cells of hair pulp of hair follicle are the stem cells of hair, stem cell of sebaceous glands, and finally, stem cells of sweat glands and their ducts. [ 11 ]…”

Section: S Tem C Ell C ...mentioning

confidence: 99%

“…Keratinocytes support the adjacent cells such as melanocytes, Merkel cells, and Langerhans cells [ Figure 3 ]. [ 5 11 53 54 ]…”

Section: S Upporting and P Rotecting ...mentioning

confidence: 99%

Different Cells of the Human Body

Mostafa

2022

Journal of Microscopy and Ultrastructure

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The cell is the basic structural unit of all living organisms. Most of the cells forming the human body share the basic components, but there are many categories that have specific light and electron microscopic characteristics. This review shed a light on these cell categories and their morphologies. Stem cell category is the cells responsible for the regeneration of damaged or lost cells, whereas protein-secreting cells are those responsible for the production and secretion of proteins. Protein-secreting cells have specific characters such as basophilic cytoplasm and vesicular nucleus by light microscope; these are confirmed by an electron microscope that shows rough endoplasmic reticulum, Golgi apparatus, secretory granules, and mitochondria. Steroid secreting, ion transporting, and contracting categories have specific morphology. Phagocytic cells such as macrophages and neutrophils are characterized by the presence of many lysosomes and phagosomes. Supporting cells are very important category as they not only support but also usually have another function such as myelin formation in Schwann, blood–brain barrier in astrocytes, or modification of response as in Pacinian corpuscle. Many cells showed interrelated characters between different categories, for example, phagocytic cells are able to contract to perform their function in fighting microorganism. Although we have trillions of cells, yet they only fall in some categories. Each cell category has specific morphological characters confirmed by ultrastructural characters. They all adapted to perform the desired functions.

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The effect of experimental hypothyroidism on the skin of adult male albino rats and the therapeutic role of topical triiodothyronine

Selim

Alazouny

2015

The Egyptian Journal of Histology

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Histological and immunohistochemical study on the effect of passive smoking on the skin of adult male albino rats and the possible protective role of nigella sativa oil

Cited by 3 publications

References 12 publications

Effect of Libyan Sidr honey on thyroid gland damage induced by cigarette smoke in male rats.

Effect of Libyan Sidr honey on thyroid gland damage induced by cigarette smoke in male rats.

Different Cells of the Human Body

The effect of experimental hypothyroidism on the skin of adult male albino rats and the therapeutic role of topical triiodothyronine

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