Histologic pattern, bilaterality and clinical evaluation of 957 ovarian neoplasms: A 10-year study in a tertiary hospital of eastern India

Abstract

We noted an earlier age at presentation of malignant tumors. Mature teratoma was found to be the second most common benign tumor (after serous cystadenoma). We also noted a lower percentage of endometrioid tumors. Lower number of stage IV tumors was noted, with a significant number of malignant ovarian tumors presenting at an earlier age.

Overview of ovarian masses

“…Out of the benign tumours, serous cystadenoma accounted for 49%; mucinous cystadenoma 39%; germ cell tumours 7.3%; sex cord tumours 4.9% which was comparable to study done by Pilli et al but differs from Mondel et al and Jha et al [9][10][11] In our study, mucinous tumours were on the rising trend comparable to the study done by Jha et al 10 Of all the malignant tumours serous cystadenocacinoma accounted for 50% followed by mucinous cystadenocarcinoma 33.3% which is comparable to study done by Sharadha et al and Pilli et al 8,9 All the malignant ovarian tumours were presented between 30-60 yrs of age and the maximum occurrence was between 41-50 yrs. One case of dysgerminoma presented at 35 yrs of age.…”

Retrospective study of tumor and tumor like conditions of ovary from a rural hospital in Kerala

“…Among surface epithelial tumors, serous cyst adenoma were more common followed by mucinous cyst adenoma. Similar results were shown in studies by Mandal et al and Ameena Ashroff et al 7,8 We categorized surface epithelial tumors into subtypes based on microscopic examination and correlating with gross clinical and radiological findings. In case of serous cyst adenoma, lining of cysts was single layer of cuboidal epithelium whereas papillae of serous cyst adenocarcinoma showed stratification of epithelial lining with nuclear atypia, mitotic activity, and stromal invasion.…”

Histological Patterns of Ovarian Neoplasms – A Five Year Experience in North-East India

“…In another study from Eastern India, the median age for malignant lesion was 48 years. [1] A higher median age of 60-65 years for malignant lesions had been reported from western countries and from southern and western part of India. [6,7,8] Malignant epithelial and sex cord stromal tumors were found to be more common after 50 years, while germ cell tumors were more prevalent before age of 20 years.…”

“…[16] In a study from eastern India endometrioid tumors (malignant type) comprised of 4.2% of all malignant ovarian tumors and in our study it is only 2.4%. [1] This may be a reflection of geographic variation of diseases.…”

“…Ovarian malignancy is second most common cancer of female reproductive system. [1] It is the fourth leading cause of death among cancer deaths in females and more predominantly after 3 rd decade. [2,3] Sixty percent of ovarian tumors in first two decades of life are germ cell tumors accounting two-third of ovarian cancers.…”