2013
DOI: 10.1590/s0100-204x2013000800026
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Histologia hepática e produção em tanques-rede de tilápia-do-nilo masculinizada hormonalmente ou não masculinizada

Abstract: Resumo -O objetivo deste trabalho foi avaliar o desempenho e a sanidade da estrutura hepática de tilápia-do-nilo, masculinizada hormonalmente ou não masculinizada, criada em tanques-rede com dois níveis proteicos. Tilápias-do-nilo da linhagem Tailandesa (total de 2.400), com peso médio inicial de 127 g, foram distribuídas em delineamento inteiramente casualizado, com quatro tratamentos, em arranjo fatorial 2×2, correspondente aos grupos de tilápias masculinizadas hormonalmente ou não masculinizadas e ao teor p… Show more

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Cited by 8 publications
(5 citation statements)
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“…Therefore, liver histology is an important biomarker for evaluating the effects of xenobiotics [30]. One of the histopathological findings when analyzing the group treated with EHELf was cytoplasmic vacuolization, a fact that was also shown in the study by Gayão et al [31], who attributed this phenomenon to the possible accumulation of lipids, thus impairing liver metabolism.…”
Section: Discussionmentioning
confidence: 70%
“…Therefore, liver histology is an important biomarker for evaluating the effects of xenobiotics [30]. One of the histopathological findings when analyzing the group treated with EHELf was cytoplasmic vacuolization, a fact that was also shown in the study by Gayão et al [31], who attributed this phenomenon to the possible accumulation of lipids, thus impairing liver metabolism.…”
Section: Discussionmentioning
confidence: 70%
“…As dietas com maior teor de energia afetam a morfologia e o arranjo celular das células hepáticas. Assim, quando a energia da dieta excede a capacidade dos hepatócitos de oxidar os ácidos graxos, a célula apresenta seu núcleo deslocado para a periferia (Caballero et al, 2004;Gayão et al, 2013), conforme o observado nas lâminas histológicas das tilápias deste estudo. De acordo com Kumar et al (2008) Estes comprometimentos na fisiologia hepática dos peixes, associados às condições de estresse em sistemas de criação intensiva, provocam depleção da imunocompetência dos animais, favorecendo o surto de enfermidades por agentes etiológicos oportunistas (Belo et al, 2014).…”
Section: Discussionunclassified
“…The negative effect of the use of this steroid has been proven in the liver tissue of fish (Ahmad et al 2002;Gayão et al 2013;Hasheesh et al 2011). The main liver alterations described in the literature are an increase of the cell volume, the disarrangement of the cordonal disposition, increase in vesicles in the hepatocytes (Gayão et al 2013), diffused vacuolar degeneration, and congestion (Hasheesh et al 2011). Furthermore, DNA fragmentation in the hepatic tissues of fish fed methyltestosterone were reported (Hasheesh et al 2011;Khalil et al 2011).…”
Section: Discussionmentioning
confidence: 99%
“…Considering that the hormone 17 alpha-methyltestosterone is an anabolic agent, the masculinized fish consequently show a higher weight gain (Karsli et al 2014;Khalil et al 2011;Vick and Hayton 2001). The survival, however, is significantly lower when compared to fish that receive diets without the hormone (Gayão et al 2013). The decreased survival of fish larvae can be associated with the structural alterations of important organs such as the liver (Hasheesh et al 2011), which is already overloaded by high protein and lipid content of the prepared diets (Furuya 2010), or can be associated with biochemical alterations (Ahmad et al 2002;Hasheesh et al 2011).…”
Section: Introductionmentioning
confidence: 99%