Hip fractures among older people in Iceland between 2008 and 2012

Skúladóttir, Sigrún Sunna; Guðmundsdóttir, Elísabet Eik; Mogensen, Brynjólfur; Masdottir, Helga Rosa; Guðmundsdóttir, Hlíf; Jonsdottir, Lovisa Agnes; Sigurthorsdottir, Ingibjörg; Torfadóttir, Jóhanna E.; Thorsteinsdottir, Thordis

doi:10.1016/j.ijotn.2018.06.001

Cited by 4 publications

(2 citation statements)

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“…However, the effect of gender on mortality after hip fracture is debatable. Male gender has been reported by many authors to be a risk factor for increased mortality after hip fracture 8 , 15 , 33 – 38 , 43 , 46 , 47 .…”

Section: Discussionmentioning

confidence: 99%

Mortality incidence and its determinants after fragility hip fractures: a prospective cohort study from an Egyptian level one trauma center

et al. 2021

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Background: Fragility hip fracture is a common condition with serious consequences. Most outcomes data come from Western and Asian populations. There are few data from African and Middle Eastern countries. Objective: The primary objective was to describe mortality rates after fragility hip fracture in a Level-1 trauma centre in Egypt. The secondary objective was to study the causes of re-admissions, complications, and mortality. Methods: A prospective cohort study of 301 patients, aged > 65 years, with fragility hip fractures. Data collected included sociodemographic, co-morbidities, timing of admission, and intraoperative,ostoperative, and post-discharge data as mortal- ity, complications, hospital stay, reoperation, and re-admission. Cox regression analysis was conducted to investigate factors associated with 1-year mortality. Results: In-hospital mortality was 8.3% (25 patients) which increased to 52.8% (159 patients) after one year; 58.5% of the deaths occurred in the first 3-months. One-year mortality was independently associated with increasing age, ASA 3-4, cardiac or hepatic co-morbidities, trochanteric fractures, total hospital stay, and postoperative ifection and metal failure. Conclusion: Our in-hospital mortality rate resembles developed countries reports, reflecting good initial geriatric health- care. However, our 3- and 12-months mortality rates are unexpectedly high. The implementation of orthogeriatric care after discharge is mandatory to decrease mortality rates. Keywords: Fragility hip fractures; trochanteric fractures; mortality rate.

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Section: Discussionmentioning

confidence: 99%

Mortality incidence and its determinants after fragility hip fractures: a prospective cohort study from an Egyptian level one trauma center

et al. 2021

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“…(6,7) Most hip fractures are caused by low-impact trauma that occurs after falling from standing height (6,8) with a gender ratio of around one male for every two to three females. (1,9,10) Vitamin D deficiency is a known risk factor for osteoporosis (11) and observational studies have consistently reported positive associations between 25-hydroxyvitamin D (25(OH)D) with bone mineral density (BMD) (12,13) and a lower risk of incidence hip fractures. (14) However, the efficacy of vitamin D supplementation alone as a preventive measure has been somewhat uncertain with randomized controlled trials (RCTs) showing no clear benefits on hip fractures incidence.…”

Section: Introductionmentioning

confidence: 99%

Serum 25-Hydroxy-Vitamin D Status and Incident Hip Fractures in Elderly Adults: Looking Beyond Bone Mineral Density

Skúladóttir

Ramel

Eymundsdottir³

et al. 2020

Journal of Bone and Mineral Research

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Observational studies have consistently reported a higher risk of fractures among those with low levels of serum 25-hydroxyvitamin D (25(OH)D). Emerging evidence suggests that low serum 25(OH)D levels may increase the rate of falls through impaired physical function. Examine to what extent baseline measures of volumetric bone mineral density (vBMD), absolute bone mineral content (BMC), and markers of physical function may explain incident hip fractures in older adults with different serum levels of 25(OH)D. A prospective study of 4309 subjects (≥66 years) recruited between 2002 and 2006 into the Age, Gene/Environment Susceptibility-Reykjavik (AGES-Reykjavik) study. Hip fractures occurring until the end of 2012 were extracted from hospital records. Prevalence of serum 25(OH)D deficiency (<30 nmol/L), inadequacy (30-<50 nmol/L), and sufficiency (≥50 nmol/L) was 6%, 23%, and 71% for males; and 11%, 28%, and 53% for females, respectively. Female participants had ~30% lower absolute BMC compared to males. Serum 25(OH)D concentrations were positively associated with vBMD and BMC of the femoral neck and markers of physical function, including leg strength and balance. Those who had deficient compared to sufficient status at baseline had a higher age-adjusted risk of incidence hipfractures with hazard ratios (HRs) of 3.1 (95% confidence interval [CI], 1.9-5.2) and 1.8 (95% CI, 1.3-2.5) among males and females, respectively. When adjusting for vBMD and measures of physical function, the association was attenuated and became nonsignificant for males (1.3; 95% CI, 0.6-2.5) but remained significant for females (1.7; 95% CI, 1.1-2.4). Deficient compared to sufficient serum 25(OH)D status was associated with a higher risk of incident hip fractures. This association was explained by poorer vBMD and physical function for males but to a lesser extent for females. Lower absolute BMC among females due to smaller bone volume may account for these sex-specific differences.

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Characteristics of incidence hip fracture cases in older adults participating in the longitudinal AGES-Reykjavik study

et al. 2020

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Hip fractures among older people in Iceland between 2008 and 2012

Cited by 4 publications

References 20 publications

Mortality incidence and its determinants after fragility hip fractures: a prospective cohort study from an Egyptian level one trauma center

Mortality incidence and its determinants after fragility hip fractures: a prospective cohort study from an Egyptian level one trauma center

Serum 25-Hydroxy-Vitamin D Status and Incident Hip Fractures in Elderly Adults: Looking Beyond Bone Mineral Density

Characteristics of incidence hip fracture cases in older adults participating in the longitudinal AGES-Reykjavik study

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