Hip fractures: A worldwide problem today and tomorrow

Melton, L. Joseph

doi:10.1016/8756-3282(93)90341-7

Cited by 410 publications

(192 citation statements)

References 40 publications

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“…in 35 patients, while the right limb was fractured in 33 cases. The prevailing mechanism of trauma was simple falls, which occurred in 58 cases, followed by high falls (6) and car accidents (4 Men and women showed a similar mortality rate, with no statistically significant difference (p > 0.05) in both groups. The recovery of free or crutch-supported ambulation ability was statistically superior (p < 0.05) in patients with physiological scores higher or equal to the overall average.…”

Section: Abstract: Femur Femoral Fractures Agedmentioning

confidence: 73%

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Evolução funcional nas fraturas da extremidade proximal do fêmur

2009

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Objectives: To assess the functional capacity evolution and the physiologic score in patients with proximal femoral end fractures, as well as to compare the final results of the treatment provided to the several pre-fracture variables. Materials and Methods: A prospective study with patients over 40 years old diagnosed with proximal femoral fracture. The patients were submitted to a pre-established protocol and followed up on an outpatient basis for a period of one year. Results: 68 patients were assessed (27 men and 41 women), with a mean age of 75,84 years. 83,82% were submitted to surgical treatment. The early mean physiologic score was 17,16 points All authors state no potential conflict of interest concerning this article

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Section: Abstract: Femur Femoral Fractures Agedmentioning

confidence: 73%

“…They are associated to a reasonable functional disability, reduced independence, quality of life and, particularly, to a reduced life expectation. [3][4][5] Osteoporosis is a risk factor related to this kind of fracture. 6 Fractures of the femoral proximal end in an aged population is a public health problem throughout the world.…”

Section: Introductionmentioning

confidence: 99%

Evolução funcional nas fraturas da extremidade proximal do fêmur

2009

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“…8 Depending on the specific type of implant, cut-out rates vary between 1.1% and 6.3%. 9,10 Given that the absolute number of osteoporosis-related proximal femur fractures will increase with future demographic changes, 11 further improvement of implant fixation is urgently needed.…”

Section: Introductionmentioning

confidence: 99%

Biomechanical evaluation of a new augmentation method for enhanced screw fixation in osteoporotic proximal femoral fractures

et al. 2006

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A biomechanical investigation on eight pairs of human cadaver proximal femurs was performed to evaluate the impact of a new augmentation method on the internal fixation of osteoporotic proximal femur fractures. The study focused on enhancing implant purchase to reduce the incidence of implant cut-out in osteoporotic bone. In a left-right comparison, a conventional hip screw fixation (control) was compared to the new cement augmentation method. After bone bed preparation through high pressure irrigation to remove fat, blood, and bone debris, the bones were augmented with low viscosity polymethylmethacrylate (PMMA) cement.Step-wise fatigue testing was performed by cyclically loading the femoral heads in a physiological manner, beginning at 1,500 N and increasing 500 N every 5,000 cycles to 4,000 N, and continuously monitoring head displacement. Failure was defined as >5.0 mm head displacement. The head displacement at 2,000 N was significantly smaller (p ¼ 0.018) for the augmented group as compared to the conventionally treated bones (0.09 AE 0.01 mm vs. 0.90 AE 0.32 mm; mean AE SEM). The displacement rate at the second load step was significantly higher (p ¼ 0.018) for the conventionally treated bones as compared to the augmented ones. All of the nonaugmented specimens failed during testing, where 50% of the augmented specimens did not fail. The promising results of these experiments suggest that this new standardized irrigation/augmentation method enhances the implant anchorage and offers a potential solution to the problem of implant cut-out in osteoporotic metaphyseal bone. ß

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“…The ultimate outcome of osteoporosis is fracture, the most serious of that is hip fracture in terms of morbidity, mortality and economic costs [1][2].…”

Section: Introductionmentioning

confidence: 99%

Variation in the PTH Gene, Hip Fracture, and Femoral Neck Geometry in Elderly Women

et al. 2010

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Running title: PTH gene and hip geometry 2(25) ABSTRACT Purpose: Parathyroid hormone (PTH) is a principal regulator of calcium homeostasis.Previously, we studied single nucleotide polymorphisms (SNPs) present in the major genes in the PTH pathway (PTH, PTHrP, PTHR1, PTHR2) in relation to bone mineral density (BMD) and fracture incidence. We found that haplotypes of the PTH gene were associated with fracture risk independent of BMD. In this present study, we evaluated the relationship between PTH haplotypes and femoral neck bone size. Methods:Hip structure analysis (HSA) and BMD of the femoral neck was assessed by DXA in elderly women from the Malmö Osteoporosis Prospective Risk Assessment (OPRA) study.Data on hip fracture, sustained as the result of low trauma after the age of 45 years, was also analysed. Haplotypes derived from six polymorphisms in the PTH locus were analysed in 750 women.

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Hip fractures: A worldwide problem today and tomorrow

Cited by 410 publications

References 40 publications

Evolução funcional nas fraturas da extremidade proximal do fêmur

Evolução funcional nas fraturas da extremidade proximal do fêmur

Biomechanical evaluation of a new augmentation method for enhanced screw fixation in osteoporotic proximal femoral fractures

Variation in the PTH Gene, Hip Fracture, and Femoral Neck Geometry in Elderly Women

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