“…Use of a combination of ( P , C , P )Ir pincer complex and stoichiometric B(C 6 H 5 ) 3 was also proved to be effective for inducing the C=O bond cleavage 17 . In contrast, Ru complexes for the selective cleavage of the C–N bond of amides were intensively studied by Ikariya (( P , N H)Ru) 18–21 , Milstein ([ P ,( N , N ) bpy ]Ru, where bpy = bipyridine; ( N , N ) bpy = bipyridine nitrogens) 22–25 , Bergens ([( P , N H 2 )( P , N H 2 )]Ru) 26–28 , Leitner/Klankermayer, ((triphos)Ru) 15 , and Beller (( P , N H, N )Ru) 29 . Milstein’s milestone discovery, in which deprotonation at the 2-(pyridyl)methylene unit in the ( P , N
py , P)Ru pincer complexes induces an active catalyst 30 , has had a great impact on the ensuing molecular design of hydrogenation catalysts (py = pyridine; N
py = pyridine nitrogen).…”