Highly sensitive cadmium sulphide quantum dots as a fluorescent probe for estimation of doripenem in real human plasma: application to pharmacokinetic study

Abstract

Thioglycolic acid-capped cadmium sulphide quantum dots (TGA-CdS QDs) as a fluorescent sensor have been synthesized and utilized as a fluorescent probe for the estimation of doripenem (DOR) in human plasma.

Fabrication of novel quantum dots for the estimation of COVID-19 antiviral drug using green chemistry: application to real human plasma

“…The quantum yield (QY) of PA@QDs was studied via single point method 11 using the following equation: …”

Interaction properties of biosynthesized cadmium sulphide quantum dots with human serum albumin: further investigation of antibacterial activities and sensing applications

“…From Equation 2, the QY for the CdS–GT QDs was calculated to be 0.29 (Figure S1), which was found to be very close to the reported literature values. [ 45,46 ]…”

“…From Equation 2, the QY for the CdS-GT QDs was calculated to be 0.29 (Figure S1), which was found to be very close to the reported literature values. [45,46] To decipher the structural properties of the synthesized CdS-GT QDs, a powder X-ray diffraction (P-XRD) experiment was performed.…”

A bio-analytically validated HPLC-UV method for simultaneous determination of doripenem and ertapenem in pharmaceutical dosage forms and human plasma: a dual carbapenem regimen for treatment of drug-resistant strain of Klebsiella pneumoniae

“…Five hundred microliters from human plasma were spiked with 1.0 mL of the stock solutions of the studied drugs. 14 One milliliter of methanol was added for protein precipitation, vortex mixed and the supernatant solution was isolated and diluted to 10 mL with distilled water. Afterward centrifuged at 4000 rpm for 20 min.…”